Autism Science

Genomic Technology Reveals Hundreds of Autism Gene Mutations

Source: 
Laboratory Equipment
Date Published: 
December 20, 2012
Abstract: 

ASF SAB member Dr. Joe Buxbaum on his new gene discoveries using high-throughput sequencing:
"By identifying the many genetic roots of this disorder, we can better understand its biology, which in turn will allow us to develop more tailored treatments for individuals. It is a transformative time for genetic research in autism."

Functional magnetic resonance imaging of autism spectrum disorders

Source: 
Dialogues in Clinical Neuroscience
Date Published: 
December 10, 2012
Abstract: 

Dr. Gabriel Dichter presents a new review of fMRI research in ASD, noting common themes of atypical activation and functional connectivity in the brain.

FMRP Targets Distinct mRNA Sequence Elements to Regulate Protein Expression

Source: 
Nature
Date Published: 
December 12, 2012
Abstract: 

Researchers link Fragile X syndrome protein to 93 genes that have been implicated in ASD. Lead investigator says the findings may lead to more detailed genetic tests.

Prenatal Versus Postnatal Sex Steroid Hormone Effects on Autistic Traits in Children at 18 to 24 Months of Age

Source: 
Molecular Autism
Date Published: 
December 11, 2012
Abstract: 

Cambridge researchers are investigating the link between pre- and postnatal hormone levels and autistic traits later in life.

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

Source: 
Science
Date Published: 
November 15, 2012
Abstract: 

De novo mutations in six genes may contribute to 1% of simplex ASD cases.