Diagnosis

Researchers find autism more common with low birth weight

Source: 
Philadelphia Inquirer
Date Published: 
October 17, 2011
Abstract: 

Autism is far more common in low-birth-weight babies than the general population, researchers are reporting, a significant finding that nevertheless raises more questions than it answers and illustrates how little is known about a group of disorders that affect nearly 1 percent of American children.

Diagnosing Autism At A Younger Age Could Lead To Earlier Interventions

Source: 
Medical News Today
Date Published: 
October 16, 2011
Abstract: 

Autism is normally diagnosed between the ages of 2 and 3, but new research is finding symptoms of autism spectrum disorders in babies as young as 12 months.

The Accuracy Of Autism Diagnosis In Children With Down Syndrome Validated By New Findings

Source: 
Medical News Today
Date Published: 
October 6, 2011
Abstract: 

New findings from a 16-year study confirm that the Diagnostic and Statistic Manual of Mental Disorders (DSM), the gold-standard for the classification of mental health conditions, can be used to accurately identify autism spectrum disorders (ASD) in children with Down syndrome, according to research from Kennedy Krieger Institute.

Multivariate Searchlight Classification of Structural Magnetic Resonance Imaging in Children and Adolescents with Autism

Source: 
Biological Psychiatry
Date Published: 
September 5, 2011
Abstract: 

Multiple brain regions, including those belonging to the default mode network, exhibit aberrant structural organization in children with autism. Brain-based biomarkers derived from structural magnetic resonance imaging data may contribute to identification of the neuroanatomical basis of symptom heterogeneity and to the development of targeted early interventions.

Distinct features of autistic brain revealed in novel Stanford/Packard analysis of MRI scans

Source: 
Stanford University
Date Published: 
September 2, 2011
Abstract: 

Researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital have used a novel method for analyzing brain-scan data to distinguish children with autism from typically developing children. Their discovery reveals that the gray matter in a network of brain regions known to affect social communication and self-related thoughts has a distinct organization in people with autism.

Prevalence and Correlates of Autism in a State Psychiatric Hospital

Source: 
Left Brain - Right Brian
Date Published: 
August 24, 2011
Abstract: 

This study estimated the ASD prevalence in a psychiatric hospital and evaluated the Social Responsiveness Scale (SRS) combined with other information for differential diagnosis. Chart review, SRS and clinical interviews were collected for 141 patients at one hospital. Diagnosis was determined at case conference. Receiver operating characteristic (ROC) curves were used to evaluate the SRS as a screening instrument. Chi-squared Automatic Interaction Detector (CHAID) analysis estimated the role of other variables, in combination with the SRS, in separating cases and non-cases. Ten percent of the sample had ASD. More than other patients, their onset was prior to 12 years of age, they had gait problems and intellectual disability, and were less likely to have a history of criminal involvement or substance abuse. Sensitivity (0.86) and specificity (0.60) of the SRS were maximized at a score of 84. Adding age of onset <12 years and cigarette use among those with SRS <80 increased sensitivity to 1.00 without lowering specificity. Adding a history substance abuse among those with SRS >80 increased specificity to 0.90 but dropped sensitivity to 0.79. Undiagnosed ASD may be common in psychiatric hospitals. The SRS, combined with other information, may discriminate well between ASD and other disorders.

Attention deficit, autism share genetic risk factors

Source: 
SFARI
Date Published: 
August 22, 2011
Abstract: 

People with autism and attention deficit hyperactivity disorder (ADHD) share some of the same underlying genetic risk factors, according to a study published this month in Science Translational Medicine. This is one of the first studies to find risk variants that are common to both disorders.
In searching for rare copy number variations (CNVs) — deletions and duplications in genetic material — in people with ADHD, the researchers found more than a dozen regions that include genes implicated in bipolar disorder, schizophrenia, intellectual disability and autism.

Most Adults with Autism Go Undiagnosed - New Findings, UK

Source: 
Medical News Today
Date Published: 
May 4, 2011
Abstract: 

Dr Brugha, who is also a consultant psychiatrist working in the NHS with the Leicestershire Partnership NHS Trust, said none of the cases with autism found in the community survey throughout England knew that they were autistic or had received an official diagnosis of autism or asperger syndrome.

Children Conceived in Winter have a Greater Risk of Autism, Study Finds

Source: 
Medical News Today
Date Published: 
May 5, 2011
Abstract: 

An examination of the birth records of the more than 7 million children born in the state of California during the 1990s and early 2000s has found a clear link between the month in which a child is conceived and the risk of that child later receiving a diagnosis of autism. Among the children included in the study, those conceived during winter had a significantly greater risk of autism, the study found.

Prevalence of Autism Spectrum Disorders in a Total Population Sample

Source: 
Autism Science Foundation Blog
Date Published: 
May 9, 2011
Abstract: 

A long-awaited study of autism prevalence in Korea came out today in the The American Journal of Psychiatry. Results showed a much higher prevalence estimate than previously found, along with a large fraction of the autistic students previously unidentified and being educated in regular education programs.