Family

Parents Turn Their Skills to Furthering Autism Research

Source: 
SFARI
Date Published: 
May 9, 2013
Abstract: 

ASF President Alison Singer is featured in this article on how parent advocates help advance autism research.

Bridges and Barriers to Successful Transitioning as Perceived by Adolescents and Young Adults With Asperger Syndrome

Source: 
Journal of Pediatric Nursing
Date Published: 
March 28, 2013
Abstract: 

This thematic content analysis examined the expectations, and perceived facilitators of and barriers to transition to community as reported by adolescents and young adults with Asperger syndrome.

Autism Risk Across Generations A Population-Based Study of Advancing Grandpaternal and Paternal Age

Source: 
JAMA Psychiatry
Date Published: 
March 20, 2013
Abstract: 

Recently published in JAMA Psychiatry, this study put forth a new autism risk factor: advanced grandpaternal age. Compared to men who had children between 20 and 24, men who fathered a child at 50+ were 1-2 times more likely to have a grandchild with autism. The findings suggest some autism risk factors can accumulate over generations.

Rate of de novo mutations and the importance of father's age to disease risk.

Source: 
PubMed
Date Published: 
August 23, 2012
Abstract: 

These observations shed light on the importance of the father's age on the risk of diseases such as schizophrenia and autism.

De novo gene disruptions in children on the autistic spectrum.

Source: 
PubMed
Date Published: 
April 26, 2012
Abstract: 

FMRP-associated genes are under greater purifying selection than the remainder of genes and suggest they are especially dosage-sensitive targets of cognitive disorders.

Association of Maternal Exposure to Childhood Abuse With Elevated Risk for Autism in Offspring

Source: 
JAMA Psychiatry
Date Published: 
March 20, 2013
Abstract: 

This study examined the relationship between maternal childhood abuse and autism in children in a large population-based sample. Maternal abuse was significantly associated with increased autism risk even after researchers controlled for perinatal risk factors, including gestational diabetes, smoking during pregnancy, preeclampsia, exposure to intimate partner violence and premature birth.

Mother's Drive Helps Research on Rare Autism-linked Mutation

Source: 
SFARI
Date Published: 
March 14, 2013
Abstract: 

A mother with two sons with autism helps advance research on neuroligin-4 mutations.

Changes to Children's Study Threaten its Value, Experts Say

Source: 
SFARI
Date Published: 
March 7, 2013
Abstract: 

Autism researchers and advocates are concerned about changes to the recruitment strategy of the National Children’s Study, which aims to enroll 100,000 pregnant women, monitor environmental exposures, and examine gene-environment interactions in the women and their children. The changes, which include forgoing door-to-door recruitment, may limit the generalizability of the findings.

Parent-child Interactions in Autism: Characteristics of Play

Source: 
Autism
Date Published: 
February 4, 2013
Abstract: 

Researchers examine parent-child dyads during structured and free play and find that that joint engagement lasts longer when parents engage their child at or slightly above the child's current level of play. Parents of children with autism often find it difficult to estimate their child's level, which can result in parents engaging at too high of a level and shortening the interaction.

The Modified Checklist for Autism in Toddlers: Reliability in a Diverse Rural American Sample

Source: 
Journal of Autism and Developmental Disorders
Date Published: 
February 6, 2013
Abstract: 

Researchers at Virginia Tech examine M-CHAT performance in a very low socio-economic status setting and find it lacks internal consistency across ethnic and educational groups. Caregivers who reported a low maternal educational level or with minority status were more likely to mark items suggestive of autism compared to those with higher maternal education or non-minority status