Treatments

Popular Autism Diet Does Not Demonstrate Behavioral Improvement

Source: 
Science Daily
Date Published: 
May 20, 2010
Abstract: 

A popular belief that specific dietary changes can improve the symptoms of children with autism was not supported by a tightly controlled University of Rochester study, which found that eliminating gluten and casein from the diets of children with autism had no impact on their behavior, sleep or bowel patterns.

Mutation Could Point Tourette Treatment

Source: 
Wall Street Journal
Date Published: 
May 6, 2010
Abstract: 

Researchers identified a rare genetic mutation that may open a new avenue for treating Tourette syndrome in a study published Wednesday that examined a family in which the father and all eight children suffer from the neurological disorder.

The family's mutation affected a gene required to produce histamine. Pharmaceutical companies are already developing drugs for other conditions that target the brain's histamine system. The study's researchers are planning a clinical trial of adults with Tourette to see if those drugs would help control the motor and vocal tics that characterize the condition.

New Research Raises Hope that Autism Effects May Be Reversible

Source: 
Medical News Today
Date Published: 
April 22, 2010
Abstract: 

A new study by researchers at The George Washington University School of Medicine and Health Sciences' Department of Biochemistry and Molecular Biology raises hope that autism may be more easily diagnosed and that its effects may be more reversible than previously thought. Researchers have identified potentially removable chemical tags (called "methyl groups") on specific genes of autistic individuals that led to gene silencing. They also observed these changes in cells derived from blood, opening the way to molecular screening for autism using a blood test.

New Study Of Autism Reveals a 'DNA tag' Amenable To Treatment

Source: 
EurekAlert
Date Published: 
April 8, 2010
Abstract: 

A new discovery raises hope that autism may be more easily diagnosed and that its effects may be more reversible than previously thought. In a new study appearing online in The FASEB Journal, scientists have identified a way to detect the disorder using blood and have discovered that drugs which affect the methylation state ("DNA tagging") of genes could reverse autism's effects. This type of drug is already being used in some cancer treatments.

Intensive Treatment Found To Be Highly Effective

Source: 
Newswise
Date Published: 
April 6, 2010
Abstract: 

Results of a randomized clinical trial found an innovative multi-component summer social development program to be effective in improving the social performance of children with high-functioning autism spectrum disorders.

Moderators, Mediators,and Other Predictors of Risperidone Response in Children with Autistic Disorder and Irritability

Source: 
Journal of Childhood and Adolescent Psychopharmacology, Arnold et al
Date Published: 
April 2010
Year Published: 
2010

The National Institute of Mental Health (NIMH) Research Units on Pediatric Psychopharmacology (RUPP) Autism Network found an effect size of d = 1.2 in favor of risperidone on the main outcome measure in an 8-week double-blind, placebo-controlled trial for irritability in autistic disorder. This paper explores moderators and mediators of this effect.  This study found the benefit-risk ratio of risperidone is better with greater symptom severity. Risperidone can be individually titrated to optimal dosage for excellent response in the majority of children. Weight gain is not necessary for risperidone benefit and may even detract from it. Socioeconomic advantage, low prolactin, and absence of co-morbid problems nonspecifically predict better outcome. Mineral interactions with risperidone deserve further study.

Reading Remediation Seems to Rewire the Brain

Source: 
US News & World Report
Date Published: 
February 26, 2010
Abstract: 

Scientists studying the anatomy of children's brains during reading discovered something rather unexpected: Remedial training for poor readers results in a growth of white matter tracts in the brain, and the increase correlates with the level of improvement in sounding out words.

Autism and Schizophrenia: Research Builds on Genetic Link

Source: 
Medical News Today
Date Published: 
February 24, 2010
Abstract: 

A genetic link between schizophrenia and autism is enabling researchers to study the effectiveness of drugs used to treat both illnesses. Dr. Steve Clapcote from the University of Leeds's Faculty of Biological Sciences will be analyzing behavior displayed by mice with a genetic mutation linked to schizophrenia and autism and seeing how antipsychotic drugs affect their behavioral abnormalities.

Gene Mutation is Linked to Autism-Like Symptoms in Mice, Reseachers Find

Source: 
Science Daily
Date Published: 
February 24, 2010
Abstract: 

When a gene implicated in human autism is disabled in mice, the rodents show learning problems and obsessive, repetitive behaviors, researchers at UT Southwestern Medical Center have found. The researchers also report that a drug affecting a specific type of nerve function reduced the obsessive behavior in the animals, suggesting a potential way to treat repetitive behaviors in humans

Music Training Enhances Brainstem Activity to Speech Sounds

Source: 
Science Daily
Date Published: 
February 22, 2010
Abstract: 

At a Feb. 20 press briefing held during the American Association for the Advancement of Science annual meeting, a Northwestern University neuroscientist argued that music training has profound effects that shape the sensory system and should be a mainstay of K-12 education. Kraus presented her own research and the research of other neuroscientists suggesting music education can be an effective strategy in helping typically developing children as well as children with developmental dyslexia or autism more accurately encode speech.