Submitted by Anonymous on February 22, 2012 - 09:38
February 22, 2012
Rhonda Charles is a 2010 ASF Grant Winner and a PhD Student in the Department of Genetics and Genomic Sciences at the Mt. Sinai School of Medicine. Ms. Charles' work focuses on the AVPR1A gene, which affects social behavior and anxiety in autism spectrum disorder. Her ASF- funded study puts the human AVPR1A gene into a mouse model, a key step that must occur before we can introduce pharmacological treatments for individuals with autism affected by AVPR1A gene mutations.
A new study from the Infant Brain Imaging Network, which includes researchers at the Center for Autism Research at The Children's Hospital of Philadelphia (CHOP), found significant differences in brain development starting at age 6 months in high-risk infants who later develop autism, compared to high-risk infants who did not develop autism.
A new study published in PLoS Genetics uses a combination of genetic and neurobiological approaches to confirm that synaptic mutations increase the risk of autism spectrum disorders (ASDs) and underlines the effect for modifier genes in these disorders.
Older maternal and paternal age are jointly associated with having a child with autism, according to a recently published study led by researchers at The University of Texas Health Science Center at Houston (UTHealth).
New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.
Researchers at Oregon Health & Science University have discovered that a molecule critical to the development and plasticity of nerve cells -- brain-derived neurotrophic factor (BDNF) -- is severely lacking in brainstem neurons in mutations leading to Rett syndrome, a neurological developmental disorder.
Results were released yesterday from the Pennsylvania Autism Needs Assessment, which includes feedback from 3,500 Pennsylvania caregivers and adults with autism, making it the largest study of its kind in the nation.
Concerns that proposed changes to autism criteria in the upcoming Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) will exclude many individuals from diagnosis and treatment are unfounded, says the American Psychiatric Association (APA).