Autism and Epilepsy Cases Share Mutations

Published October 15, 2013 in Simons Foundation Autism Research Institute

About one-third of people with autism suffer from epilepsy. This overlap suggests that the two disorders may have a common origin a theory borne out by examples of shared genetics. Mutations in GABRB3, a brain receptor linked to autism, are prevalent in severe childhood epilepsy, according to a study published in Nature. The study also found that many of the spontaneous mutations found in children with epilepsy overlap with those linked to autism and fragile X syndrome.

http://sfari.org/news-and-opinion/in-brief/2013/genetics-autism-epilepsy-cases-share-mutations

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