Better animal model, new drug target discovered at Duke

Published May 10, 2016

Scientists at Duke Health, including ASF fellow Alexandra Bey, recently showed that targeting a brain receptor in mice with a specific type of autism could ease repetitive behaviors and improve learning in some animals.

This report, published in Nature Communications, suggests that among more than a dozen different lines of mice developed around the world to mirror autism caused by mutations to the SHANK3 gene, Duke researchers are the first to create a mouse in which that gene has been completely eliminated.  To read more about this study click the press release HERE.

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