Mutation Could Point Tourette Treatment

Published May 6, 2010 in Wall Street Journal

Researchers identified a rare genetic mutation that may open a new avenue for treating Tourette syndrome in a study published Wednesday that examined a family in which the father and all eight children suffer from the neurological disorder.The family’s mutation affected a gene required to produce histamine. Pharmaceutical companies are already developing drugs for other conditions that target the brain’s histamine system. The study’s researchers are planning a clinical trial of adults with Tourette to see if those drugs would help control the motor and vocal tics that characterize the condition.

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