Reversal of Autism-Like Behaviors and Metabolism in Adult Mice with Single-Dose Antipurinergic Therapy

Translational Psychiatry
Date Published: 
June 17, 2014

Researchers at UC San Diego have discovered that suramin, a drug that was originally developed to treat African sleeping sickness, reverses autism-like social behaviors in mice. This study proposes that the social difficulties and metabolism issues found in individuals with ASD could be improved with the use of suramin — even in adults. While suramin has not been tested in humans, these findings could direct future research for autism therapies.