Research by Topic: Autoimmune

Problematic Antibodies Affecting Brain Development During Pregnancy Could Help Explain 1/4 of Cases of Autism

Published July 9, 2013 in Translational Psychiatry

Antibodies found almost exclusively in mothers with children who have autism have a certain anitbody that may be affecting brain development during pregnancy. The same study says that these antibodies could account for nearly 1/4 of all cases of autism.

http://www.nature.com/tp/journal/v3/n7/abs/tp201350a.html

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A Better Early Blood Test for Autism

Published December 5, 2012 in The Sacramento Bee

Researchers at Boston’s Children Hospital claim a new blood test outperforms existing genetic tests for diagnosing ASD.

http://www.sacbee.com/2012/12/05/5033734/a-better-early-blood-test-for.html

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New Evidence Links Immune Irregularities to Autism

Published July 17, 2012

Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as autism a decade ago. Since then, studies of postmortem brains and of individuals with autism, as well as epidemiological studies, have supported the correlation between alterations in the immune system and autism spectrum disorder.

http://www.sciencedaily.com/releases/2012/07/120717141010.htm

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Bone-marrow Transplant Reverses Rett Syndrome in Mice

Published March 17, 2012 in Nature Magazine

A bone-marrow transplant can treat a mouse version of Rett syndrome, a severe autism spectrum disorder that affects roughly 1 in 10,00020,000 girls born worldwide (boys with the disease typically die within a few weeks of birth).

Bone-marrow transplant reverses Rett syndrome in mice

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Autism may be linked to abnormal immune system characteristics and novel protein fragment

Published January 3, 2012 in MedicalXpress

Immune system abnormalities that mimic those seen with autism spectrum disorders have been linked to the amyloid precursor protein (APP), reports a research team from the University of South Florida’s Department of Psychiatry and the Silver Child Development Center.

Autism may be linked to abnormal immune system characteristics and novel protein fragment

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Vaccines largely safe, U.S. expert panel finds

Published August 25, 2011 in Reuters

After a close review of more than 1,000 research studies, a federal panel of experts has concluded that vaccines cause very few side effects, and found no evidence that vaccines cause autism or type 1 diabetes.The report, issued on Thursday by the Institute of Medicine, part of the National Academies of Sciences, is the first comprehensive report on vaccine side effects since 1994.

http://www.reuters.com/article/2011/08/25/us-vaccines-idUSTRE77O4ZE20110825

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The Tragedy Of The Fraudulent MMR Autism Link, A Personal Story

Published February 7, 2011 in Medical News Today

Medical journalist recaps his struggle to determine if vaccinations caused his son to be diagnosed with Asperger’s Syndrome concluding that it would not have made the slightest bit of difference if we had refused to vaccinate when our son was small, claiming any conspiracy theories are not based on any compelling data.

http://www.medicalnewstoday.com/articles/215841.php

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Parental Autoimmune Diseases Associated with Autism Spectrum Disorders in Offspring

Published November 1, 2010 in Epidemiology, Keil, Daniels et al

Studies have suggested associations between immune response and idiopathic disorders (such as autism). This study explores associations between parental autoimmune disorders and children's diagnosis of autism by linking. The study found associations between parental autoimmune disorders and autism spectrum disorders, suggesting parental autoimmune disorders may represent a pathway that warrants more detailed investigation.

http://journals.lww.com/epidem/Abstract/2010/11000/Parental_Autoimmune_Diseases_Associated_With.10.aspx

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Study Links Immune Protein to Abnormal Brain Development

Published October 15, 2010 in Medical News Today

Insight into the role that MHC plays in the nervous system and may enhance our understanding of the factors that can contribute to neuropsychiatric disorders like autism and schizophrenia. Increased levels of a protein called major histocompatibility complex, or MHC, in fetal neurons may be a factor development of autism or schizophrenia.

http://www.medicalnewstoday.com/articles/204693.php

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How Immune Response in Pregnancy May Lead to Brain Disfunction in Offspring

Published October 14, 2010 in Science Daily

A pregnant woman’s immune response to viral infections may induce subtle neurological changes in the unborn child that can lead to an increased risk for neurodevelopmental disorders including schizophrenia and autism.

http://www.sciencedaily.com/releases/2010/10/101012141924.htm

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Immune System Troubles Could Spark Behavior Woes

Published May 27, 2010 in Bloomberg Businessweek

In the first scientific illustration of exactly how some psychiatric illnesses might be linked to an immune system gone awry, researchers report they cured mice of an obsessive-compulsive condition known as “hair-pulling disorder” by tweaking the rodents’ immune systems.

http://www.businessweek.com/lifestyle/content/healthday/639578.html

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Vaccines: The Reality Behind The Debate

Published April 12, 2010 in Parents Magazine

Wary parents want to protect their child from any possible risk. It’s time to inject a dose of reality into the rumor-driven debate.

http://www.parents.com/baby/health/vaccinations/vaccines-the-reality-behind-the-debate/

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