Research by Topic: Irritability

Gluten Sensitivities May Cause GI Problems in Children with Autism

Published June 18, 2013 in PLoS One

A subset of children with autism displays increased immune reactivity to gluten, the mechanism of which appears to be distinct from that in celiac disease. The increased anti-gliadin antibody response and its association with GI symptoms points to a potential mechanism involving immunologic and/or intestinal permeability abnormalities in affected children.

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0066155

Filed under: , , , , , ,


Antioxidants For Autism

Published June 1, 2012 in Biological Psychiatry

A specific antioxidant supplement containing N-Acetylcysteine, or NAC may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children’s Hospital that involved 31 children with the disorder.

http://www.science20.com/news_articles/antioxidants_autism-90568

Filed under: , , , ,


Training Parents Is Good Medicine for Children With Autism Behavior Problems, Study Suggests

Published February 24, 2012 in Science Daily

Children with autism spectrum disorders who also have serious behavioral problems responded better to medication combined with training for their parents than to treatment with medication alone, Yale researchers and their colleagues report in the February issue of Journal of the American Academy of Child & Adolescent Psychiatry.

Training Parents Is Good Medicine for Children With Autism Behavior Problems, Study Suggests

Filed under: , , , , , , ,


ASF-funded study: JADD Challenging behaviors frequent in autistic children with and without GI problems; therefore behaviors are unlikely to predict GI problems in children with ASDMaenner et al.

Published October 25, 2011 in Journal of Autism and Developmental Disorders

Association Between Behavioral Features and Gastrointestinal Problems Among Children with Autism Spectrum DisorderMatthew J. Maenner • Carrie L. Arneson • Susan E. Levy • Russell S. Kirby • Joyce S. Nicholas • Maureen S. DurkinJournal of Autism and Developmental Disorders | DOI 10.1007/s10803-011-1379-6 Copyright: Springer Science+Business Media, LLC 2011 Abstract : Recent reports suggest certain […]

http://www.springerlink.com/content/b23217521067w850/

Filed under: , , , ,


Association Between Behavioral Features and Gastrointestinal Problems Among Children with Autism Spectrum Disorder

Published October 25, 2011 in Journal of Autism and Developmental Disorders - Maenner, M.J. et al.

Recent reports suggest certain behaviors among children with autism spectrum disorders (ASD) may indicate underlying gastro-intestinal (GI) problems, and that the presence of these behaviors may help alert primary care providers to the need to evaluate a child with ASD for GI problems. The purpose of this population-based study of 487 children with ASD, including […]

http://www.springerlink.com/content/b23217521067w850/

Filed under: , , , , ,


Minocycline Promising in Fragile X Syndrome

Published September 7, 2010 in Medscape Today

Parents of children with fragile X syndrome report that minocycline led to positive improvements in language, attention levels and behavior. They also report experiencing adverse side effects such as mild gastrointestinal issues and some increased irritability.

http://www.medscape.com/viewarticle/728141?src=emailthis

Filed under: , , , , , , , , ,


GI Problems and Autism Link? Experts Say No

Published April 16, 2010 in ABC News

British Medical Journal examined the continued belief by many of a possible connection between the developmental disorder and the chronic inflammatory bowel disease, that was first dubbed “autistic enterocolitis” by British physician Dr. Andrew Wakefield. But beyond Wakefield’s account, the evidence of any connection between bowel disease and autism is slim, the editorial stated.

http://abcnews.go.com/Health/Autism/stomach-pains-autism/story?id=10388309&page=1

Filed under: , ,


Moderators, Mediators,and Other Predictors of Risperidone Response in Children with Autistic Disorder and Irritability

Published April 1, 2010 in Journal of Childhood and Adolescent Psychopharmacology, Arnold et al

The National Institute of Mental Health (NIMH) Research Units on Pediatric Psychopharmacology (RUPP) Autism Network found an effect size of d = 1.2 in favor of risperidone on the main outcome measure in an 8-week double-blind, placebo-controlled trial for irritability in autistic disorder. This paper explores moderators and mediators of this effect. This study found […]

http://www.ncbi.nlm.nih.gov/pubmed/20415603

Filed under: , , ,