Research by Topic: Oxytocin

Precision medicine presents: OXYTOCIN!!!

Published November 7, 2016

Overall, the scientific research examining the efficacy of oxytocin treatment in autism spectrum disorder has been mixed. On a previous podcast, studies on the way the oxytocin receptor was turned on and off were explained, which may account for variability in treatment response. This week, two studies in Japan show that specific mutations in the oxytocin […]

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Oxytocin enhances brain function in children with autism

Published December 24, 2013 in Proceedings of the National Academy of Sciences

"Following intranasal administration of oxytocin (OT), we measured, via functional MRI, changes in brain activity during judgments of socially (Eyes) and nonsocially (Vehicles) meaningful pictures in 17 children with high-functioning autism spectrum disorder (ASD). OT increased activity in the striatum, the middle frontal gyrus, the medial prefrontal cortex, the right orbitofrontal cortex, and the left […]

http://www.ncbi.nlm.nih.gov/pubmed/?term=24297883

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Oxytocin and Serotonin May Not be Rewarding Social Interactions in Autistic Brain

Published September 11, 2013 in Nature

In the brain, oxytocin and serotonin work together to make social interactions pleasurable, rewarding, and worth repeating. A new study in the journal Nature shows that in individuals with autism, these rewarding functions may not be occurring properly, making social interaction uncomfortable.

http://www.nature.com/nature/journal/v501/n7466/full/nature12518.html

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New Study Deciphers Potential Roles of Oxytocin in Brain Function

Published August 4, 2013 in Nature

An NYU study explored the role of oxytocin in the brain’s ability to filter wanted stimuli from unwanted stimuli. The researchers suggest that the neurohormone, oxytocin, is not only used to reduce unwanted background noise but also plays a key function in strengthening desired signals.

http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12330.html

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Oxytocin-Looking Beyond the Love Drug

Published August 10, 2012 in Wall Street Journal

Important work from ASF SAB Member Kevin Pelphrey of the Yale Child Study Center.

http://online.wsj.com/article/SB10000872396390443991704577577100471163434.html

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