Tuberous Sclerosis, Fragile X Share immune Changes

Simons Foundation Autism Research Initiative
Date Published: 
May 6, 2014

Two autism-related disorders — fragile X syndrome and tuberous sclerosis complex — share disruptions in the immune system despite major differences in the individual genes affected, reports a study in Molecular Autism. An abnormally regulated immune system is linked to some forms of autism, but exactly how genetic changes in the immune system contribute to autism is unclear.