Oxytocin Treatment Trial

Dec 3 2013
America/New York
Location: 
Children's Hospital of Philadelphia
Description
Previous research suggests that the release of the hormone oxytocin is important for social learning and social functioning - core deficits of autism spectrum disorders (ASD). This study will test whether oxytocin, when administered as a nasal spray, can increase social learning when combined with a computer game intervention, which is designed to help children with ASD recognize faces and facial expressions.
 
If families agree to participate, the participation may include up to eight visits to the Center for Autism Research over the course of approximately two weeks. Families will have fewer visits if they decide to complete treatment sessions at home. The study will require at least two visits to the Center for Autism Research, including the first treatment visit and a follow-up visit. Participants will take part in social, behavioral, intelligence (IQ), and other developmental testing and medical monitoring. Parents will be asked to answer questions over the phone, in person, and on paper. During five of the visits, participants will receive either intranasal oxytocin or placebo (inactive nasal spray) and play computerized games designed to improve social perceptual skills. Children who take part will receive a comprehensive report based on diagnostic, social, behavioral, and IQ testing.   
 
There is no cost to participate. Participants will be paid for their time and reimbursed for their travel costs.
 
 
Eligibility
Males between the ages of 12 and 17 with a diagnosis of autism, Asperger Syndrome, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) may take part. Children currently taking medications are eligible to take part, provided no changes are made to the dosage within one month of study participation or during the course of the study.
 
 
Contact Information
Fam Baguio
(267) 426-9242