Published in: 2012

September, 2012

This study systematically reviewed evidence regarding vocational interventions for individuals with Autism Spectrum Disorder (ASD) between the ages of 13 and 30 years.

September, 2012
J Am Acad Child Adolesc Psychiatry

This study conducted an observational study of 192 families caring for a young person (aged 14 to 24 years) with a childhood diagnosis of ASD or ADHD (n = 101 and n = 91, respectively) in the United Kingdom. A modified stress-appraisal model was used to investigate the correlates of caregiver burden as a function of family background (parental education), primary stressors (symptoms), primary appraisal (need), and resources (use of services).

September 19, 2012
Sci Transl Med

Research on animal models of fragile X syndrome suggests that STX209, a GABA(B) agonist, might improve neuro-behavioral function in affected patients.

October, 2012
J Am Acad Child Adolesc Psychiatry

This study was carried out to examine the efficacy of a 12-week, low-intensity, parent-delivered intervention for toddlers at risk for autism spectrum disorders (ASD) aged 14 to 24 months and their families.

October 2012
Journal of the American Academy of Child & Adolescent Psychiatry

Contrary to their hypothesis, Sally Rogers and colleagues found that toddlers with ASD in a brief, parent-delivered ESDM program did not make greater gains or show reduced core ASD symptoms compared to autistic toddlers in a community ESDM program. Study strongly suggests number of intervention hours and younger age at initiation are key to maximizing intervention benefits, even for 1 and 2 year olds. Authors say, “the ‘wait and see’ approach to early ASD must be replaced by an ‘act now’ mentality.”

October 17, 2012
Disability and Health Journal

ASF Grantee Matthew Maenner and colleagues developed the Waisman Activities of Daily Living (W-ADL) Scale to measure daily living skills of adolescents and adults with developmental disabilities. The scale is a free and efficient tool for surveys and epidemiological research.

October 1, 2012
The American Journal of Psychiatry

Substantial revisions to the DSM-IV criteria for autism spectrum disorders (ASDs) have been proposed in efforts to increase diagnostic sensitivity and specificity. This study evaluated the proposed DSM-5 criteria for the single diagnostic category of autism spectrum disorder in children with DSM-IV diagnoses of pervasive developmental disorders (PDDs) and non-PDD diagnoses.

November, 2012

This study assessed parent-reported elopement occurrence and associated factors among children with Autism Spectrum Disorders (ASD)s.

November 11, 2012
J Am Acad Child Adolesc Psychiatry

This report describes the the resulting EEG activity from randomized clinical trial. These clinical trial included a developmental behavioral intervention.

May, 2012
J Am Acad Child Adolesc Psychiatry

This study examines the cognitive and language outcomes of children with an autism spectrum disorder (ASD) over a 5-year period after receiving targeted early interventions that focused on joint attention and play skills.

May, 2012
Epilepsy Behav

This study was designed to assess AED effect in a placebo-controlled double-blind cross-over study. Levetiracetam (LEV) was chosen based on clinical evidence.

May, 2012
J Autism Dev Disord

This study describes the services used by 152 children aged 24-60 months with autism, report family out-of-pocket expenses and productivity losses, and explore the relationship between family characteristics and costs.

March, 2012
Am J Psychiatry

The effects of fluoxetine and placebo on repetitive behaviors and global severity were compared in adults with autism spectrum disorders (ASDs).

March, 2012
J Autism Dev Disord

This study conducted a randomized trial with citalopram (an anti-depressant drug) in children with Pervasive developmental disorders (PDDs).

March 22, 2012
PLoS Genetics

A new study of autism published today in PLoS Genetics has discovered abnormal gene activity and gene deletions in the same brain region that also has a 67% overabundance of brain cells. This region – the prefrontal cortex—is involved in social, emotional, communication and language skills. The finding brings new understanding of what early genetic abnormalities lead to excess brain cells and to the abnormal brain wiring that cause core symptoms in autism. Importantly, the study also shows that gene activity abnormalities in autism change across the lifespan.

March 1, 2012
Cold Spring Harb Perspect Biol

The human studies unveiled the sensitivity of cognitive function to precise levels of different proteins.

June, 2012
Appl Psychophysiol Biofeedback

The goal of this study was to investigate whether reaction time, error rate, post-error reaction time change, error related negativity, and error related positivity will show positive changes following 12-week long slow frequency repetitive Transcranial Magnetic Stimulation(rTMS) over dorsolateral prefrontal cortex (DLPFC) in high functioning children with ASD.

June 1, 2012
Biol Psychiatry

The goal of this pilot study was to assess the feasibility of using oral N-acetylcysteine (NAC), a glutamatergic modulator and an antioxidant, in the treatment of behavioral disturbance in children with autism.

January, 2012
J Child Psychol Psychiatry

Assess the effects of a preschool-based Joint Attention (JA)-intervention.

January, 2012
Res Dev Disabil

This study examined the effects of a modified Mindfulness-based therapy (MBT) protocol (MBT-AS) in high-functioning adults with ASD.

February, 2012
J Am Acad Child Adolesc Psychiatry

Children with Pervasive Developmental Disorders (PDDs) have social interaction deficits, delayed communication, and repetitive behaviors as well as impairments in adaptive functioning. Many children actually show a decline in adaptive skills compared with age mates over time.

December 26, 2012
December 21, 2012

UCSD researchers suggest genes linked to autism have higher mutation rates than other genes.

December 12, 2012
J Sleep Res

This study demonstrates that adding behavioural intervention to melatonin treatment seems to result in a better treatment response, at least in the short term.

August, 2012
J Consult Clin Psychol

This study investigated the effectiveness of public preschool teachers implementing a validated intervention (the Joint Attention and Symbolic Play/Engagement and Regulation intervention; JASP/ER) on a core deficit of autism, initiating joint attention.

August, 2012
J Autism Dev Disord

Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD).

April, 2012
J Child Psychol Psychiatry

This study compared two interventions for improving the social skills of high functioning children with autism spectrum disorders in general education classrooms. One intervention involved a peer-mediated approach (PEER) and the other involved a child-assisted approach (CHILD).

April, 2012
J Child Psychol Psychiatry

Fifty children with high-functioning Autism Spectrum Disorder (ASD) and anxiety were randomized to group Cognitive Behavioral Theory (CBT) or treatment-as-usual (TAU) for 12 weeks.

Interagency Autism Coordinating Committee

Published in: 2011

September 2011
American Journal of Psychiatry
October 25, 2011
Journal of Autism and Developmental Disorders - Maenner, M.J. et al.
November 2011
Journal of the American Geriatrics Society
May 2011
Biol Psychiatry, Di Martino et al.
March 2011
Journal of Molecular Psychiatry, Gai et al.
June 8, 2011
Science Translational Medicine
June 2011
Environ Health Perspect, Volke et al.
January 2011
Acta Psychiatrica Scandanavia, M.-J Dealberto
January 2011
Archives of General Psychiatry, Pierce et al.
February 2011
Archives of Pediatric & Adolescent Medicine, Shattuck et al.

Published in: 2010

July 2010
Diability and Health Journal, Rice et al
January 2010
Pediatrics, Dawson, Rogers, Munson, Smith, Winter, Greeson, Donaldson, and Varley
January 2010
Environmental Health Perspectives, Hertz-Picciotto, Green, Delwiche, Hansen, Walker, Pessah
December 2010
Journal of Neuroscience, Zikopoulos and Barbas
December 2010
Journal of the American Medical Association, Giulivi et al
December 2010
PNAS, Kaiser, Hudack, Schultz, Lee, Cheung, Berken, Deen, Pitskel, Sugrue, Voos, Saulnier, Ventola, Wolf, Klin, Vander Wyk, Pelphrey
April 2010
Journal of Childhood and Adolescent Psychopharmacology, Arnold et al

Published in: 2013

October 16, 2013

A new study brings important insights about the cellular and molecular mechanisms involved in the loss and gain of synaptic function in human neurons from patients with Phelan-McDermid syndrome and autism. It also provides encouragement that neurons derived from induced pluripotent stem cells of patients will be useful in understanding and developing treatments for neurodevelopmental and psychiatric disorders.

May, 2013
J Autism Dev Disord

This study's purpose was to investigate mortality among individuals with Autism Spectrum Disorders (ASD) ascertained during a 1980s statewide autism prevalence study (n = 305) in relation to controls.

January, 2013
J Autism Dev Disord

In the current study, a developmental adaptation of pivotal response treatment was piloted via a brief parent training model with three infants at-risk for autism.

January 2013
J Autism Dev Disord

In this study, functional magnetic resonance imaging was used to identify the neural correlates of successful response to Pivotal response treatment (PRT) in two young children with Autism Spectrum Disorder (ASD).

Published in: 2009

May 2009
Molecular Psychiatry, Strom, Stone, Bosch, Merriman, Cantor, Geschwind, and Nelson
May 2009
International Meeting for Autism Research
June 2009
PLOS Genetics, Bucan M, Abrahams BS, Wang K, Glessner JT, Herman EI, et al.
June 2009
Archives of General Psychiatry, King, Hollander, Sikich, McCracken, Scahill, Bregman, Donnelly, Anagnostou, Dukes, Sullivan, Hirtz, Wagner, Louise Ritz; for the STAART Psychopharmacology Network
January 2009
Pediatrics, Tozzi AE, Bisiacchi P, Tarantino V, De Mei B, D'Elia L, Chariotti F, Salmaso S.
February 2009
PNAS, Sur, Tropea, Giacometti, et al.
August 2009
Pediatrics, Ibrahim, Voigt, Katusic, Weaver, and Barbaresi

Published in:

January, 2013
Journal of Autism and Developmental Disorders

Though neither ASD nor DD was associated with influenza, both were associated with maternal fever during pregnancy. However, the fever-associated ASD risk was attenuated among mothers who reported taking antipyretic medications but remained elevated for those who did not.

Neuropshcyopharmacology, Bear, Dolen et al
Journal of Child Psychology and Psychiatry, Gernsbacher, Sauer et al
Brain Behavior Immunology, Martin, Ashwood, Braunschweig, Cabanlit, Van de Water, Amaral
Autism, Mouridsen, Bronnum-Hansen, et al
New England Journal of Medicine, Weiss, Shen, et al
Journal of Neuroimmunology, Singer, Morris, Gause, Gillin, Crawford, Zimmerman

Published in: 2008

January 2008
American Journal of Human Genetics, Alarcon, Abrahams, et al.
December 2008
American Journal of Human Genetics, Arking, Cutler, et al
Neurotoxicology, Braunschweig, Ashwood, et al
Genes Development, Choi, DiNardo, et al
Archives of General Psychiatry, Fombonne
Neuropsychology Review, Helt, Kelley, et al
Human Molecular Genetics, Kumar, KaraMohamed, et al
American Journal of Public Health, Mandell, Wiggins, et al
American Journal of Human Genetics, Marshall, Noor, et al
Journal of Developmental and Behavioral Pediatrics, Pinto-Martin, Young, Mandell, Poghosyan, Giarelli, Levy

Published in: 2007