Autism News

Maternal Antibodies from Mothers of Children with Autism Alter Brain Growth and Social Behavior Development in the Rhesus Monkey

Source: 
Translational Psychiatry
Date Published: 
July 9, 2013
Abstract: 

Antibodies directed against fetal brain proteins of 37 and 73 kDa molecular weight are found in approximately 12% of mothers who have children with autism spectrum disorder (ASD), but not in mothers of typically developing children. This finding has raised the possibility that these immunoglobulin G (IgG) class antibodies cross the placenta during pregnancy and impact brain development, leading to one form of ASD.

Electronic Medical Records May Reveal Subgroup of Autism

Source: 
Simons Foundation Autism Research Initiative
Date Published: 
January 16, 2013
Abstract: 

Some children diagnosed with autism may fall into distinct subgroups based on their symptoms and other diagnoses, researchers report in the January issue of Pediatrics. The three subgroups identified in the study show some overlap in symptoms, but each is characterized by a distinct set of features: seizures, general health problems such as gastrointestinal distress, and psychiatric problems. The analysis relied on the largest database yet, and looked at symptoms over time.

Lack of Training Begets Autism Diagnosis Bottleneck

Source: 
Simons Foundation Autism Research Institute
Date Published: 
January 13, 2014
Abstract: 

One of the frustrations that parents of children with autism most commonly voice is the long wait for a diagnosis. In the meantime, the children grow up and out of the critical period for early intervention. The scenario for adults seeking an autism diagnosis is even grimmer, as there are fewer practitioners experienced in caring for adults with autism than in caring for children with the disorder. There are few comprehensive statistics about waiting times, but the bottlenecks in access to autism diagnosis and care are widely acknowledged. These concerns are spurring the medical community to take a hard look at the failings of professional training in contributing to the problem.

Catalog of Symptoms Aims to Unravel Autism Diversity

Source: 
Simons Foundation Autism Research Initiative
Date Published: 
January 8, 2014
Abstract: 

Researchers have standardized labels for nearly 300 traits of autism, drawn from 24 diagnostic tests for the disorder, they reported in Neuroinformatics. They can use these terms to search for certain traits among large catalogs of the genetics and symptoms of people with autism. The new study aims to build a defined list, or ontology, of the traits these tests assess. The goal is to allow researchers to compare results across different diagnostic tests and identify the same features, regardless of the test used. The new tool can also help classify individuals with autism into subgroups, which may reflect different causes of the disorder.

Reward Affects Motor Function in Rett

Source: 
Simons Foundation Autism Research Institute
Date Published: 
January 10, 2014
Abstract: 

The motor problems seen in Rett syndrome may be the result of deficits in a pathway that mediates reward in the striatum, a brain region that coordinates movement, according to a study published in Brain Structure and Function. Studies have shown that loss of MeCP2 in the front of the brain is sufficient to lead to Rett-like symptoms in mice. The forebrain includes the striatum, which integrates information from other brain regions to help plan and coordinate movement. The new study found that mice that model Rett syndrome have significantly less dopamine — a chemical messenger that mediates reward — in the striatum than controls do. The study suggests that changes in dopamine levels influence neural circuits in the striatum that regulate motor function.

Senses of Sight and Sound Separated in Children with Autism

Source: 
Vanderbilt University
Date Published: 
January 14, 2014
Abstract: 

Like watching a foreign movie that was badly dubbed, children with autism spectrum disorders (ASD) have trouble integrating simultaneous information from their eyes and their ears, according to a Vanderbilt study. The study, led by Mark Wallace, Ph.D., director of the Vanderbilt Brain Institute, is the first to illustrate the link and strongly suggests that deficits in the sensory building blocks for language and communication can ultimately hamper social and communication skills in children with autism.

Study Shows Children with Autism only 10 Percent More Likely to be Using Complementary and Alternative Medicine

Source: 
Journal of Developmental and Behavioral Pediatrics
Date Published: 
January 11, 2013
Abstract: 

A new study from the Journal of Developmental and Behavioral Pediatrics looked at nearly 600 children with ASD and with developmental delays. 40 percent of the children with autism in the study were using complementary and alternative medicine (CAM). While this may seem like a high percentage, it is only ten percent higher than the rate of nonautistic children in the study using CAM. The most common forms of complementary treatments reported were dietary supplements.

First Business Summit on Employing Adults with Autism Convenes January 27-29 in North Carolina with Focus on Unique Role for Small Businesses in Closing the Autism Employment Gap

Date Published: 
January 8, 2014
 
 
CHAPEL HILL, NC (January 8, 2014) – As the U.S. prepares for a tsunami of young adults with autism who will enter the job market over the next decade, autism specialists and business leaders will assemble in Chapel Hill, NC on January 27-29 for the first summit to press for more small businesses solutions to what is already an unemployment crisis affecting tens of thousands of these individuals.
 
Convened by Extraordinary Ventures, Inc. (EV), a North Carolina non-profit organization that is a pioneer in creating small businesses that employ adults across the autism spectrum, the summit – Employing Adults on the Autism Spectrum: A Conference on Pioneering Small Business Models – is especially timely now that 90 percent of people with autism spectrum disorder (ASD) are either unemployed or underemployed and an estimated 500,000 additional Americans with ASD will be seeking employment over the next decade. Because today’s job market is unprepared for this wave of prospective employees, the conference will showcase 14 of the most innovative small business models now employing these workers to elevate the role of local entrepreneurs and small businesses as a critical solution to the autism job gap.
 
“For the autism community, this national conference is nothing short of the turning point in addressing the unemployment crisis now affecting tens of thousands of adults with autism and realizing their potential as truly successful and contributing members of society,” said Gregg Ireland, Senior Vice President and Portfolio Counselor at Capital World Investors and father of a 23-year old son with autism who founded Extraordinary Ventures in 2007. “Especially during a time of budget tightening andfederal and state government cut-backs, the answer to this problem rests with us and our commitment to advocate for small business solutions across the country. The goal is to spark a national movement where an increasing number of small businesses and entrepreneurs create self-sustaining businesses to meet the needs of their local residents while providing a range of jobs that match the skills of people with autism and developmental disabilities.”
 
To build the case for small business solutions to the unemployment crisis affecting adults with autism, the conference will focus on the strategies used by the leading innovators in the field, such as EV, that without government funding operates five different businesses, or “Ventures,” which collectively employ 40 young adults with autism or a developmental disability in the Chapel Hill area. After trying and failing to sustain its operations through a traditional non-profit structure, EV assembled a team of recent college graduates – entrepreneurs seeking to create a suite of small micro-businesses – and transformed a struggling start-up into an effective and profitable company that operates backwards from traditional models, structuring each “Venture” around the tasks that young adults with autism are capable of doing, such as businesses where there is a specified flow and series of routine steps. This means mapping out all the tasks required to operate a successful business, then laying out each step in the process and providing employees with the visual cues, diagrams and other tools so they can follow these steps. 
 
“EV was founded on the core belief that adults with autism and developmental disabilities are capable of holding a job and doing meaningful work, and what our employees are accomplishing every day is proof that this is true,” Ireland explained. “Regardless of whether they are high, mid- or lower-functioning employees, EV offers each employee a job based on what he or she can contribute to the business. Our business proposition is to break everything down, organize each business operation to fit our workers,and not to be afraid of risk or to try something new.” 
 
Currently, EV runs a thriving laundry service for students attending the University of North Carolina, operates a transit bus cleaning operation that works five days a week, rents space at its headquarters building for meetings and social events, produces and markets premium handmade scented candles sold in gift shops, Whole Foods and online, and operates an office solutions service. Cited by Autism Speaks as one of America’s leading small business models for employing adults with autism, this sustainable business model is proving so successful in Chapel Hill that groups in New York and Detroit are replicating the model and other communities may soon follow suit. 
 
Along with EV, the conference will feature the successes of a range of non-profit organizations and small businesses that are using entrepreneurial principles to provide employment opportunities for adults on the autism spectrum. Organizations that will be featured are: 
 
Arthur & Friends, based in Newton, NJ, which operates greenhouses that employ disabled adults who grow and market hydroponic produce
Aspiritech, headquartered in Chicago, which employs high-functioning adults with autism as part of a workforce that conducts domestic software testing and provides other quality assurance (QA) services
Autistic Global Initiative in San Diego, whose members on the autism spectrum provide professional and consulting services to a range of industries
AutonomyWorks, also in Chicago, which leverages the unique talents and abilities of people with autism to deliver technology services, such as website maintenance, reporting and quality assurance, to companies of all sizes
Beneficial Beans, a Phoenix-based café that trains adults with autism spectrum disorders and provides employment opportunities
Inclusion Films Workshop in Burbank, CA, which provides vocational training and an entry-level knowledge of film and TV production to adults with developmental disabilities 
Lee & Marie’s Cakery in Miami Beach, which works with the University of Miami/Nova Southeastern University’s Center for Autism and Related Disabilities to provide job training and employment to adults across the autism spectrum
nonPareil Institute in Plano, TX, which provides training in technology services, particularly app development, and employment to individuals with ASD
Poppin’ Joe’s Gourmet Kettle Korn based in Louisburg, KS, which was started to create an opportunity for Joe Steffy, a young adult with Down syndrome and autism spectrum disorder, to run his own business. Today, the company employs several part-time workers and sells snacks at fairs, craft shows, car shows and events throughout Kansas and Missouri
Rising Tide Car Wash, in Parkland, FL, which created a system that breaks the car washing process into 46 distinct steps so families affected by autism can operate car washing businesses
Roses for Autism in Guilford, CT, which employs adults with ASD who cut, sort, grade and care for the roses grown on a large farm
Waggies by Maggie & Friends, based in Wilmington, DE, which employs adults with intellectual disabilities to bake, package and market all-natural dog treats
[words] Bookstore in Maplewood, NJ, which operates as a training facility so adults with autism can learn retail job skills and move on to larger companies
 
“While these small business solutions are different in size and approach, each already has far-reaching effects and can be replicated or customized to create the ripple effect needed for real change,” Ireland said. “On a national scale, EV and the other businesses that will be highlighted at this conference offer realistic models for any community seeking to expand job opportunities for adults with autism and developmental disabilities.” 
 
Extraordinary Ventures designed Employing Adults on the Autism Spectrum: A Conference on Pioneering Small Business Models in collaboration with the Adult Services team at Autism Speaks and the University of North Carolina TEACCH Autism Program. As the meeting takes place, media and interested stakeholders can follow the discussion on Twitter using #AutismEntrepreneurs. 
 
Contact: Jennifer Crawford
202-570-8174
200 S. Elliott Road, Chapel Hill, NC 27514
Extraordinaryventures.org | (919)967.1100

Duplication of Chromosome 22 Region Thwarts Schizophrenia

Source: 
Simons Foundation Autism Research Institute
Date Published: 
January 2, 2014
Abstract: 

Carrying a duplication of the 22q11.2 chromosomal region may protect against schizophrenia, suggests a study published 12 November in Molecular Psychiatry. This is the first evidence of a genetic region that lowers the risk of a disorder rather than increases it. Deletion of this part of chromosome 22 is the strongest known risk factor for schizophrenia, and is also linked to autism, attention deficit hyperactivity disorder and anxiety in childhood. Various other copy number variations (CNVs), or stretches of a chromosome that are deleted or duplicated multiple times in the genome, have been linked to schizophrenia, autism and other neurological conditions. The new study is the first to pinpoint a CNV that lowers the risk of a disorder, however.

Maternal Infection During Pregnancy and Autism Spectrum Disorders

Source: 
Journal of Autism and Developmental Disorders
Date Published: 
Jan 1, 2014
Abstract: 

Pregnant women who were diagnosed with a bacterial infection during a hospital visit were more likely to have their child be diagnosed with autism spectrum disorder, a study in the Journal of Autism and Developmental Disorders reports. "Multiple maternal infections and bacterial infections occurring during late pregnancy, particularly those diagnosed in a hospital setting, were associated with a higher risk of autism," the researchers reported.