Mutations

Multiplex Targeted Sequencing Identifies Recurrently Mutated Genes in Autism Spectrum Disorders

Source: 
Science
Date Published: 
November 15, 2012
Abstract: 

De novo mutations in six genes may contribute to 1% of simplex ASD cases.

Common Genetic Variants, Acting Additively, Are a Major Source of Risk for Autism

Source: 
Molecular Autism
Date Published: 
October 15, 2012
Abstract: 

Study finds that together, a large number of inherited, common genetic variations “of very small effect” can increase risk for autism. Suggests risk of inherited ASD is approximately 40% in simplex families and 60% in multiplex families.

Progress in Identifying the Genetic Roots of Autism

Source: 
Wall Street Journal
Date Published: 
September 25, 2012
Abstract: 

Genetic tests are beginning to shed light on the causes of some autism spectrum disorders.

Father’s Age Is Linked to Risk of Autism and Schizophrenia

Source: 
Nature
Date Published: 
August 22, 2012
Abstract: 

Older men are more likely than young ones to father a child who develops autism or schizophrenia, because of random mutations that become more numerous with advancing paternal age, scientists reported on Wednesday, in the first study to quantify the effect as it builds each year. The age of mothers had no bearing on the risk for these disorders, the study found. Full article is here - http://www.autismsciencefoundation.org/sites/default/files/nature11396.pdf.