Psychopharmacology

Genetic Architecture in Autism Spectrum Disorder.

Source: 
Current Opinion in Genetics and Development
Date Published: 
June 2012
Abstract: 

Biological pathways revealed by the deeper list of ASD genes should narrow the targets for therapeutic intervention.

Why Are There So Many Unsubstantiated Treatments in Autism?

Source: 
Research in Autism Spectrum Disorders
Date Published: 
December 27, 2012
Abstract: 

An estimated 32-92% of parents use complementary/alternative treatments for their children with ASD despite the lack of scientific evidence for the efficacy of these methods. In this article, researchers issue a call for a standardized way to select and evaluate treatments. Barriers to successful treatment, including high costs, limited availability, parental compliance and poor recommendations from professionals are discussed.

New Supplement in Pediatrics: Improving Health Care for Children and Youth With Autism and Other Neurodevelopmental Disorders

Source: 
Pediatrics
Date Published: 
November 1, 2012
Abstract: 

Access full articles on interventions, sleep and GI problems, health care coverage and more.

Roche and Seaside Therapeutics Enter Alliance to Develop Pharmacological Treatments for Autism

Source: 
http://www.marketwatch.com/story/roche-seaside-to-research-autism-treatments-2012-06-19?reflink=MW_news_stmp
Date Published: 
June 19, 2012
Abstract: 

Roche and Seaside Therapeutics have entered an alliance to develop pharmacological treatments for autism spectrum disorders and Fragile X Syndrome.

Special Report: New Drugs, Fresh Hope for Autism Patients

Source: 
Reuters
Date Published: 
May 31, 2012
Abstract: 

Researchers are conducting advanced trials of the first drugs expressly designed to correct the genetically induced signaling problems in the brain that result in autism. The early indications are positive enough to offer new hope for families and spark interest from drug companies.

Researchers are conducting advanced trials of the first drugs expressly designed to correct the genetically induced signaling problems in the brain that result in autism. The early indications are positive enough to offer new hope for families and spark interest from drug companies.

Antioxidants For Autism

Source: 
Biological Psychiatry
Date Published: 
June 1, 2012
Abstract: 

A specific antioxidant supplement containing N-Acetylcysteine, or NAC may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children's Hospital that involved 31 children with the disorder.

A specific antioxidant supplement containing N-Acetylcysteine, or NAC may be an effective therapy for some features of autism, according to a pilot trial from the Stanford University School of Medicine and Lucile Packard Children's Hospital that involved 31 children with the disorder.

New Clinical Study Evaluates First Drug to Show Improvement in Subtype of Autism

Source: 
EurekAlert
Date Published: 
April 26, 2012
Abstract: 

In an important test of one of the first drugs to target core symptoms of autism, researchers at Mount Sinai School of Medicine are undertaking a pilot clinical trial to evaluate insulin-like growth factor (IGF-1) in children who have SHANK3 deficiency (also known as 22q13 Deletion Syndrome or Phelan-McDermid Syndrome), a known cause of autism spectrum disorder (ASD).

Evidence behind autism drugs may be biased: study

Source: 
Reuters
Date Published: 
April 24, 2012
Abstract: 

Doctors' belief that certain antidepressants can help to treat repetitive behaviors in kids with autism may be based on incomplete information, according to a new review of published and unpublished research.

Clinical trials of new treatments for Fragile X are accepting participants

Source: 
FRAXA Research Foundation
Date Published: 
March 22, 2012
Abstract: 

Experimental new drugs, AFQ056 (an mGluR5 antagonist from Novartis) and STX209 (arbaclofen from Seaside Therapeutics) are in large scale trials.

New Research Might Help Explain How a Gene Mutation Found in some Autistic Individuals Leads to Difficulties in Processing Auditory Cues and Paying Spatial Attention to Sound.

Source: 
Science Daily
Date Published: 
February 2, 2012
Abstract: 

New research from Cold Spring Harbor Laboratory (CSHL) might help explain how a gene mutation found in some autistic individuals leads to difficulties in processing auditory cues and paying spatial attention to sound.