Treatment

Interventions Addressing Social Impairment in Autism

Source: 
Current Psychiatry Reports
Date Published: 
October 4, 2012
Abstract: 

In this new review of intervention studies targeting social impairment in autism, authors encourage researchers to design new studies that: evaluate ingredients of effective interventions (e.g., required dose for therapeutic effect); include better outcome measures that can show that meaningful improvements have happened (e.g., spontaneous social initiations; sustained interactions); and include underserved and underrepresented participant groups, such as children with comorbidities, non-English speaking children, and minimally verbal children.

Aging in Autism Spectrum Disorders: A Mini-Review

Source: 
Gerontology
Date Published: 
August 24, 2011
Abstract: 

This article addresses an important and barely researched topic: what happens to children with autism spectrum disorders when they grow old.

Effects of a Brief Early Start Denver Model (ESDM)-Based Parent Intervention on Toddlers at Risk for Autism Spectrum Disorders: A Randomized Controlled Trial

Source: 
Journal of the American Academy of Child & Adolescent Psychiatry
Date Published: 
October 2012
Year Published: 
2012
Abstract: 

Contrary to their hypothesis, Sally Rogers and colleagues found that toddlers with ASD in a brief, parent-delivered ESDM program did not make greater gains or show reduced core ASD symptoms compared to autistic toddlers in a community ESDM program. Study strongly suggests number of intervention hours and younger age at initiation are key to maximizing intervention benefits, even for 1 and 2 year olds. Authors say, “the ‘wait and see’ approach to early ASD must be replaced by an ‘act now’ mentality.”

What the DSM-5 Portends for Research, Diagnosis, and Treatment of Autism Spectrum Disorders.

Source: 
Current Psychiatry Reports
Date Published: 
September 19, 2012
Abstract: 

With the impending release of DSM-5, this article reviews proposed changes related to ASD diagnosis and discusses possible implications of DSM-5 changes on autism treatment and research.

Experimental Drug may Treat Social Withdrawal Symptoms in Individuals with Fragile X Syndrome, the Most Common Known Genetic Cause of Autism.

Source: 
Science Translational Medicine
Date Published: 
September 19, 2012
Abstract: 

Arbaclofen, also known as STX209, shows promise in its treatment of social symptoms associated with fragile x syndrome.

The Emerging Biology of Autism Spectrum Disorders

Source: 
Science
Date Published: 
September 14, 2012
Abstract: 

Autism spectrum disorders (ASD) are a genetically and phenotypically heterogeneous group of syndromes defined by fundamental impairments in social reciprocity and language development accompanied by highly restrictive interests and/or repetitive behaviors. Recent advances in genetics, genomics, developmental neurobiology, systems biology, monogenic neurodevelopment syndromes, and induced pluripotent stem cells (iPSC) are now offering remarkable insights into their etiologies and converging to provide a clear and immediate path forward from the bench to the bedside.

Dietary Supplement may Treat Rare Form of Autism

Source: 
Science
Date Published: 
September 6, 2012
Abstract: 

Researchers have uncovered a rare, genetic form of autism caused by mutations that speed up the breakdown of certain amino acids.

“Junk” DNA Holds Clues to Cancer, Autism

Source: 
Scientific American
Date Published: 
September 6, 2012
Abstract: 

With the latest annotation of the human genome, researchers have made new discoveries about common diseases

Evaluation of a Parent-Based Behavioral Intervention Program for Children with Autism in a Low-Resource Setting

Source: 
Journal of Pediatric Neuroscience
Date Published: 
January 2012
Abstract: 

Many countries do not have widely available or established resources for individuals with autism. This study from New Delhi, India examines parent-based intervention programs for children with autism in a low-resource setting.

Autism Drug Aims to Balance Brain Signals

Source: 
New Scientist
Date Published: 
September 15, 2010