Social-communicative deficits in Autism Spectrum Disorder as measured by synaptic density and mGluR5 positron emission tomography

Location: New Haven, CT - Yale University
Start Date: October 9th, 2018
End Date: March 13th, 2019

This study is designed to look at brain activity using Positron Emission Tomography (PET) in adults with Autism Spectrum Disorder (ASD). PET imaging will be used to measure specific molecules in the brain and to measure synaptic connectivity. The study will take place across two or three separate visits (one or two PET scans). The first day will consist of a brief physical exam and a 30-minute magnetic resonance imaging (MRI) scan. Up to two PET scans can be completed on a single day or different days depending on preference. Participants will be compensated $100 for the first day and up to $450 for both PET scans. Reasonable travel costs will be reimbursed.

Eligibility
To qualify for this study, individual must have IQ>80, must be their own legal guardian, and not currently prescribed anti-epileptics, benzodiazepines, or barbiturates.

Contact Information
If you are interested in participating, please contact Erin MacDonnell at autism@yale.edu or (203) 737-3439.