Autism Risk Across Generations A Population-Based Study of Advancing Grandpaternal and Paternal Age

Published March 20, 2013 in JAMA Psychiatry

Recently published in JAMA Psychiatry, this study put forth a new autism risk factor: advanced grandpaternal age. Compared to men who had children between 20 and 24, men who fathered a child at 50+ were 1-2 times more likely to have a grandchild with autism. The findings suggest some autism risk factors can accumulate over generations.