Maternal antibodies from mothers of children with autism alter brain growth and social behavior development in the rhesus monkey

Published July 9, 2013 in Translational Psychiatry

Recent studies have produced findings that suggest that immunoglobulin G (IgG) class antibodies cross the placenta during pregnancy and affect brain development. Researchers believe that this may lead to one form of ASD. The activity of IgG antibodies was monitored in groups of female rhesus monkeys during their first and second trimesters of pregnancy. Results demonstrated there were differences in white matter volume in IgG-ASD offspring, and these differences were most prominent in the frontal lobes.

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