Snippets of RNA May Reverse Symptoms of Angelman Syndrome

Published December 4, 2014 in Simons Foundation Autism Research Initiative

Small pieces of RNA restore the expression of a key gene missing in Angelman syndrome and offer the promise of a highly specific cure, researchers reported Monday in Nature. Injecting these RNA snippets into the brains of mice missing one copy of this gene, called UBE3A, reverses their memory problems.