Research by Topic: autism brainnet

What Happened This Year in Autism Research? A look back at 2018

Published January 5, 2019

This year, more than before, scientists were able to show that autism is a spectrum within a spectrum of other neuropsychiatric issues.  There are similarities across diagnoses, and genetic profiles of those with autism, ADHD, OCD, bipolar depression and schizophrenia.  There were also major accomplishments in understanding the role of the environment, behavioral and pharmacological […]

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Podcast: Reusing and recycling autism data from brain tissue

Published June 25, 2018

On this week’s podcast, data obtained from brains of people with autism is reused and re-analyzed so that a new role of mitochondria and their relationship to the activity of synapse genes could be discovered. In addition, cellular stress is seen in the brains of people with autism. What comes first? Mitochondrial dysfunction and cellular […]

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Spring 2018 Autism BrainNet newsletter available now

Published April 27, 2018

The Spring 2018 issue of the Autism BrainNet newsletter is out now! Among other news, it highlights recent research using its donated brain tissue resources in autism genetics and neuroanatomy, the science campaign Brain Awareness Week, and outreach efforts through Autism Speaks walks around the country. You can view and read this issue here.

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Podcast: Here’s to understanding why people with autism have anxiety in adolescence

Published April 2, 2018

On this week’s ASF podcast: By looking directly at the brains of people with autism, researchers at UC Davis MIND Institute, led by Dr. Thomas Avino and Dr. Cyndi Schumann, show a disruption of neuron number in the amygdala in autism. The amygdala is important because it is linked to emotion, fear and anxiety in […]

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Neurons increase in social brain region as children become adults – except in autism

Published March 20, 2018

Researchers at Autism BrainNet node UC Davis MIND Institute found that while typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults, people with ASD do not. The open access research published in PNAS studied 52 postmortem human brains, both neurotypical and […]

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Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Published February 9, 2018 in Science, Gandal, Haney, et al

Research led by Daniel Geschwind of the University of California, Los Angeles used postmortem brain tissue, including resources from Autism BrainNet, found similar gene expression patterns in the brains of those with autism, schizophrenia, and bipolar disorder. All three conditions show an activation of genes in star-shaped brain cells called astrocytes, and suppression of genes […]

Science Magazine Report

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Banking on brains for clues to autism: A Spectrum News Deep Dive

Published November 2, 2017

Banking on brains for clues to autism

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The latest on understanding the brains of people with autism

Published October 23, 2017

In a new blog post, ASF CSO Alycia Halladay explains the newest research in understanding the brains of people with autism.

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The Icahn School of Medicine at Mount Sinai and UNYTS collaborate to increase brain tissue for autism research

Published September 12, 2017

The Icahn School of Medicine at Mount Sinai (ISMMS) and Unyts, the designated organ procurement organization for the eight counties of western New York State, announced today a new agreement that will help increase and enhance the quantity of postmortem brain tissue available for critical autism research. Unyts, which coordinates all organ, eye, and tissue donation […]

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Brain tissue is used to identify commonalities across neuropsychiatric disorders

Published May 25, 2016

In a recent study published in Nature, Dr. Shannon Ellis looks past the sequence of genes and uses gene expression profiling to understand the similarities between autism, schizophrenia and bipolar disorder.  Using brain tissue from people affected with these disorders provided through the Autism BrainNet, she demonstrates a common decrease in gene expression relating to […]

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