Research by Topic: genes

ASF renews grant to expand Baby Sibs research

Published July 2, 2018

ASF is proud to announce continued support for the Baby Siblings Research Consortium (BSRC), a network of over 33 research sites around the world studying the younger siblings of people with autism. The Baby Sibs database now tracks over 5,000 younger siblings, with and without autism. The database has been used to develop more sophisticated […]

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Podcast: Reusing and recycling autism data from brain tissue

Published June 25, 2018

On this week’s podcast, data obtained from brains of people with autism is reused and re-analyzed so that a new role of mitochondria and their relationship to the activity of synapse genes could be discovered. In addition, cellular stress is seen in the brains of people with autism. What comes first? Mitochondrial dysfunction and cellular […]

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New IAN article on epigenetics and autism

Published June 5, 2018

The Interactive Autism Network published an article explaining the latest epigenetics research in autism. It highlights how environmental factors, both internal and external, affect genes and influence an individual’s development. Including findings made from Autism BrainNet tissue resources, research is demonstrating how epigenetics may play a role in the development and severity of autism. Read […]

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Podcast: Narrowing down gene and environment interactions in autism

Published January 30, 2017

With hundreds of genes, thousands of environmental factors, and now sex being variables in determining risk for autism, where should science start? Over the decades researchers have been able to start narrowing down the combinations based on specific behaviors of interest, genes, and mechanisms which may narrow down which gene, which environmental factor and which […]

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Evidence of a second-hit model supports genetic and environmental roles in autism

Published January 24, 2016

This week in Science Reports, an article showed that the risk of autism is further increased in individuals with a specific mutation on chromosome 22 when another mutation is present.  One of these mutations is in a gene that is known to be affected by different environmental factors.  Scientists are using this data to help understand […]

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