Research by Topic: risk

Genes, environment and heritability: why does it matter?

Published August 28, 2019 in ASF Podcast

This week a 5 country collaboration including the largest number of people EVER revealed 80% of the causes of autism are heritable. This is incredibly important to understand autism and move forward with research that matters to families.  What it did not do was calculate the role of gene x environment interactions which seems to […]

https://asfpodcast.org/archives/794

Filed under: , , , , , ,


Genes, environment and heritability: why does it matter?

Published July 29, 2019 in ASF Podcast

This week a 5 country collaboration including the largest number of people EVER revealed 80% of the causes of autism are heritable. This is incredibly important to understand autism and move forward with research that matters to families.  What it did not do was calculate the role of gene x environment interactions which seems to […]

https://asfpodcast.org/archives/794

Filed under: , , , , , ,


DSM5 – where are we now?

Published July 1, 2019 in ASF Pocast

Don’t be fooled, not all the studies on this week’s podcast focus on the DSM5.  But the first one, a review of a meta analysis and review of the dozens of publications that have emerged in the past 5 years around the DSM5 leads us off.  There are some people that weren’t captured by either […]

https://asfpodcast.org/archives/722

Filed under: , , , , , , ,


Vaccination Patterns in Children After Autism Spectrum Disorder Diagnosis and in Their Younger Siblings

Published June 26, 2019 in JAMA Pediatrics

IMPORTANCE: In recent years, rates of vaccination have been declining. Whether this phenomenon disproportionately affects children with autism spectrum disorder (ASD) or their younger siblings is unknown. OBJECTIVES: To investigate if children after receiving an ASD diagnosis obtain their remaining scheduled vaccines according to the Advisory Committee on Immunization Practices (ACIP) recommendations and to compare […]

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2676070

Filed under: , ,


The association between maternal use of folic acid supplements during pregnancy and risk of autism spectrum disorders in children: a meta-analysis

Published June 24, 2019 in Molecular Autism

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625821/

Filed under: , , , ,


Autism risk following antidepressant medication during pregnancy

Published June 24, 2019 in Psychological Medicine

BACKGROUND: Previous studies have examined if maternal antidepressant medication during pregnancy increase the risk of autism spectrum disorder (ASD) in the offspring, but the results have been conflicting.METHODS: In a population-based cohort of 179 007 children born in 2006 and 2007 and followed through 2014 when aged 7 and 8, we estimated relative risks (RRs) of […]

https://www.cambridge.org/core/journals/psychological-medicine/article/autism-risk-following-antidepressant-medication-during-pregnancy/20AEF7A7CDDA81E60136F4FE0A73C692#

Filed under: , , , ,


Maternal Multivitamin Intake, Plasma Folate and Vitamin B12 Levels and Autism Spectrum Disorder Risk in Offspring

Published June 24, 2019 in Paediatric and Perinatal Epidemiology

BACKGROUND: To examine the prospective association between multivitamin supplementation during pregnancy and biomarker measures of maternal plasma folate and vitamin B12 levels at birth and child’s Autism Spectrum Disorder (ASD) risk.METHODS: This report included 1257 mother-child pairs, who were recruited at birth and prospectively followed through childhood at the Boston Medical Center. ASD was defined from […]

https://onlinelibrary.wiley.com/doi/full/10.1111/ppe.12414

Filed under: , , , ,


Prenatal exposure to fever is associated with autism spectrum disorder in the boston birth cohort

Published June 24, 2019 in Autism Research

Autism spectrum disorder (ASD) is phenotypically and etiologically heterogeneous, with evidence for genetic and environmental contributions to disease risk. Research has focused on the prenatal period as a time where environmental exposures are likely to influence risk for ASD. Epidemiological studies have shown significant associations between prenatal exposure to maternal immune activation (MIA), caused by […]

https://onlinelibrary.wiley.com/doi/abs/10.1002/aur.1841

Filed under: , , , ,


Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

Published June 24, 2019 in Nature Communications

Integration of emerging epigenetic information with autism spectrum disorder (ASD) genetic results may elucidate functional insights not possible via either type of information in isolation. Here we use the genotype and DNA methylation (DNAm) data from cord blood and peripheral blood to identify SNPs associated with DNA methylation (meQTL lists). Additionally, we use publicly available […]

https://www.nature.com/articles/s41467-017-00868-y

Filed under: , , , ,


Podcast: Why the Environmental Protection Agency is important for autism

Published March 26, 2018

On this week’s podcast, highlights of a new study led by Dr. Amy Kalkbrenner of the University of Wisconsin Milwaukee published in Environmental Health Perspectives—certain air pollutants from cars and coal burning plants were associated with autism risk and severity. This scientific evidence supports policies which keep U.S. Environmental Protection Agency infrastructure intact to monitor […]

Filed under: , , , , , , , , , , ,


“Could Smoking in Pregnancy Affect a Grandkid’s Autism Risk?”

Published April 28, 2017

ASF Chief Science Officer Dr. Alycia Halladay commented on a new study on the risk of autism if an individual’s grandmother smoked during pregnancy. While the study cannot prove cause-and-effect, the researchers have discovered a link here. Click here to read more.

Filed under: , , ,


Largest ever study on parental age and autism identifies new groups with increased risk

Published June 12, 2015

A new study replicated the finding of increased risk of having a child with autism among older parents. Because of the enormous size of the study, some new risk groups were identified with regards to age, but what does these findings mean and what should parents know? Listen to the ASF podcast to find out, and hear about vocational programs that work. https://youtu.be/P4EkaYNrMjM

New study on parental age and autism: so who isn't at risk?

Filed under: , , , , ,