Research by Topic: science

Neurons increase in social brain region as children become adults – except in autism

Published March 20, 2018

Researchers at Autism BrainNet node UC Davis MIND Institute found that while typically-developing children gain more neurons in a region of the brain that governs social and emotional behavior, the amygdala, as they become adults, people with ASD do not. The open access research published in PNAS studied 52 postmortem human brains, both neurotypical and […]

Filed under: , , , , , , , , ,

CDC Study Finds 95% of Children with Autism Have One Comorbidity

Published March 14, 2018

A new study by the CDC, including Dr. Matthew Maenner, ASF Grantee ’10, found that 95% of children with autism have at least one psychiatric or medical comorbidity, which may have a role in age of first evaluation—the more comorbid conditions, the earlier the first evaluation for ASD. Read the study here.

Filed under: , , , , , , , ,

Genetic Variations on SETD5 Underlying Autistic Conditions

Published March 6, 2018

SETD5 is a master regulator of gene activity that controls the activity of potentially thousands of other downstream genes in the same cell. Researchers, supported in part by ASF, found that this gene is associated with a subtype of autism that is seen mostly in males and includes intellectual disability and facial dysmorphology. This is […]

Filed under: , , , , , , , , ,

Podcast: An ode to rats as animal models for autism

Published February 12, 2018

On this week’s podcast, a study led by Elizabeth Berg in the lab of Dr. Jill Silverman at UC Davis published in the journal Autism Research demonstrated SHANK3’s role in core social communication deficits in a rat model of autism. Rats exhibit both receptive and expressive communication. SHANK3 mutations are seen in those with Phelan-McDermid […]

Filed under: , , , , , , , , , ,

Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap

Published February 9, 2018 in Science, Gandal, Haney, et al

Research led by Daniel Geschwind of the University of California, Los Angeles used postmortem brain tissue, including resources from Autism BrainNet, found similar gene expression patterns in the brains of those with autism, schizophrenia, and bipolar disorder. All three conditions show an activation of genes in star-shaped brain cells called astrocytes, and suppression of genes […]

Science Magazine Report

Filed under: , , , , , , , , , , ,

New Autism Study is a Pain in the Calf

Published July 12, 2017

This summer, ASF will begin funding a post-doctoral fellowship to Dr. Michelle Failla at Vanderbilt University to understand the pain response in people with autism.  This study will examine both verbal responses to pain, as well as nonverbal responses like heart rate, facial expression and stress response, to a mild stimuli in adults with ASD. […]

Filed under: , , , ,

ASF Grantees and Fellows Present Research at IMFAR

Published May 10, 2017

Autism Science Foundation grantees and fellows will be giving several presentations throughout the International Meeting for Autism Research (IMFAR) in San Francisco this week. If you will be at IMFAR, see details below so you can attend their presentations. If not, see below anyway to learn about the great work ASF grantees and fellows are […]

Filed under: , , , , ,

Podcast: Putting the pieces together around group social skills interventions

Published February 6, 2017

Individual research studies are great. But even better is when someone takes these studies and puts them together to see if one study shows the same thing another does, and if they do, then is the effect size consistent? Sometimes you can only do this by going old school and pooling the data from the […]

Filed under: , , ,

Scientists studying genetic cause of autism meet with families

Published July 31, 2015

Dup15, an organization representing families with one of the most common genetic causes of autism, held their annual family and science meeting in Orlando this week. Hear more about the science on the ASF podcast.

Filed under: , , , , , , , ,

ASF Undergraduate Research Fellowships Help Build Autism Researchers

Published June 30, 2015 in ASF Blog

Veronica Kang, recipient of ASF Undergraduate Summer Research Fellowship discusses the results of her honors thesis project and the impact of ASF funding on her career. Read more on the ASF Blog here:

Filed under: , , ,