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Research by Topic: UCLA
Podcast: Reusing and recycling autism data from brain tissue
Published June 25, 2018On this week’s podcast, data obtained from brains of people with autism is reused and re-analyzed so that a new role of mitochondria and their relationship to the activity of synapse genes could be discovered. In addition, cellular stress is seen in the brains of people with autism. What comes first? Mitochondrial dysfunction and cellular […]
Filed under: Autism, autism brainnet, brain tissue, Brown University, cellular stress, featured, Fragile X, FRAXA Research Foundation, genes, mitochondria, NeuroBioBank, NIH, podcast, research, Tuberous Sclerosis, Tuberous Sclerosis Alliance, UCLA
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap
Published February 9, 2018 in Science, Gandal, Haney, et alResearch led by Daniel Geschwind of the University of California, Los Angeles used postmortem brain tissue, including resources from Autism BrainNet, found similar gene expression patterns in the brains of those with autism, schizophrenia, and bipolar disorder. All three conditions show an activation of genes in star-shaped brain cells called astrocytes, and suppression of genes […]
Filed under: Autism, autism brainnet, Autism Research, bipolar disorder, Daniel Geschwind, featured, gene expression, research, Schizophrenia, science, Science Magazine, UCLA