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GEMMA (Genome, Environment, Microbiome, and Metabolome in Autism)

January 14, 2019 - October 18, 2024

The GEMMA (Genome, Environment, Microbiome, and Metabolome in Autism) project aims to understand the many factors that contribute to the development of autism in children who have an autistic sibling.

What are the goals of the study?

The GEMMA project aims to understand how genes, the environment, gut bacteria, and the digestion of food may relate to the development of autism.

What will happen during the visit or online?

  1. Online surveys about food, health, and behavior,
  2. Behavioral assessments (on Zoom) every 6 months from ages 1 to 3,
  3. Periodic saliva, urine, stool, and blood samples (done at home/locally) until age 3,
  4. One time samples from one or both biological parents and from the sibling with ASD

How will this help families?

Your family will be contributing to research that aims to help improve the early diagnosis of autism, as well as understand the GI symptoms associated with autism. All infant participants will receive early developmental assessments from study psychologists.

Eligibility Criteria

We are recruiting infants 0-6 months old who have a full-sibling diagnosed with autism.

Contact Information

To learn more about our study or to participate, please email our coordinator Emma at mghgemma@mgh.harvard.edu or call 617-643-6918

Research Study Website
Massachusetts General Hospital -- the GEMMA Study

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