Share

Imaging Cognition and Neurodevelopment (ICAN)

July 5, 2022 - July 30, 2024

What are the goals of the study?

The purpose of this research study is to examine relationships between brain and behavior development in toddlers with and without autism who have older siblings.

What will happen during the visit or online?

Your participation would involve you coming to the Center for Autism Research at CHOP in Philadelphia with your toddler.

There are four parts involved in your participation:

  1. A remote video call interview with you and our study’s clinical psychologist.
  2. Online questionnaires which you will complete on your own time on any internet device.
  3. A behavioral evaluation of your toddler. For this part, you will first visit the Center for Autism Research with just you and your toddler. After this behavior evaluation, we will schedule a follow-up video call with you, where the psychologist will inform you about the testing results.
  4. If your child meets our criteria, we will ask you to return for an MRI scan of your toddler’s brain while they sleep.

You will be compensated for your time and effort dedicated to the study and you will be reimbursed for your travel expenses to CHOP.

How will this help families?

A focus on the earliest signs of autism is critical for families, so that children can access services and supports as early as possible. CAR researchers are using neuroimaging methods to identify brain signatures in children starting from 6 months of age onward that might be associated with autism in children with and without a family history of autism.

Eligibility Criteria

Toddlers 16-20 months old. You may qualify for our study if you or your child’s healthcare provider has concerns regarding your toddler’s development (communication, motor, behavior, or social concerns or developmental concerns). Toddlers must have older biological sibling(s) without autism.

View the study flyer here.

Contact Information
Research Study Website
Center for Autism Research at CHOP

More Research studies from this topic: Core ASD Symptoms

Autism Biomarkers Consortium for Clinical Trials
In-person participation required
Transcranial Magnetic Stimulation (TMS)
In-person participation required
Generating Effectiveness Mechanisms in RUBI (GEMs in RUBI)
In-person participation required
Intranasal Vasopressin Treatment in Children with Autism
In-person participation required
A treatment for SETD5 subtype of autism
Fully remote/online
NEUROIMAGING PREDICTORS OF IMPROVEMENT TO PIVOTAL RESPONSE TREATMENT (PRT) IN YOUNG CHILDREN WITH AUTISM
In-person participation required
Center for Brain Disease Diagnosis at the NRI
Fully remote/online In-person participation required
Neural basis of social cognition in youth with ASD and psychosis
In-person participation required
Neurodevelopmental Sleep Study
In-person participation required
San Diego State University Toddler MRI Project
In-person participation required
Exploring Mechanisms of Change in a Pilot Trial of the RUBI Program in Educational Settings
Fully remote/online
Autism Home Videos for Children
Fully remote/online
Autism face fMRI
In-person participation required
Autism Intervention Research Network on Behavioral Health
Fully remote/online
Simons Searchlight
Fully remote/online
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
In-person participation required
Aging in Autism
In-person participation required
Predicting and Optimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum Disorder (POLO)
In-person participation required
Adolescent Communication of Emotion Study
In-person participation required
Social Motivation
In-person participation required
Pivotal Response Treatment for Children with Autism Spectrum Disorders
In-person participation required
Exploring Positive and Negative Dimensions in Autism Spectrum Disorders (EXPAND)
In-person participation required
CHARGE
In-person participation required
ECHO
In-person participation required
Infant-Caregiver Synchrony in Autism
In-person participation required
MRI Study for Prediction of ASD
In-person participation required
Walking and Talking in Autism
In-person participation required
SPARK: Simons Foundation Powering Autism Research for Knowledge
Fully remote/online In-person participation required
What do you Eat?
Fully remote/online
RARE-X Data Collection Program
Fully remote/online
BRIDGE Study (Brain Indicators of Developmental Growth)
In-person participation required
Cognitive Functioning in Children
Fully remote/online
Multimodal investigation of emotional reactivity as a predictor of later psychopathology in infants at risk for ASD
In-person participation required
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
In-person participation required
Genetics of Autism in Latinx Ancestries
In-person participation required
Social Computations in Autism with Neuroimaging
In-person participation required
Social Dynamics and Early Visual Experiences
In-person participation required
Characterizing Electroencephalogram (EEG) Index of Plasticity of the Social Brain in Autism Spectrum Disorder
In-person participation required
Social Cognition in Brain and Behavior
Fully remote/online In-person participation required
Sensory Reactivity and Regulation Development
In-person participation required
Neural Mechanisms of Cognitive Inflexibility in Autism Spectrum Disorder
In-person participation required
The neuroanatomical basis for face processing deficits in autism spectrum disorder
In-person participation required
Following Language Growth in Autism at Home (FLASH)
Fully remote/online In-person participation required
WATCH Motor Development Study: Advancing Screening Tools for ASD
In-person participation required
Family-Implemented Treatment for Behavioral Inflexibility (FITBI) Project
Fully remote/online
The Investigation of Genetics Exome Research (TIGER-3)
Fully remote/online In-person participation required
Research Studying Pimavanserin in Irritability Associated with Pediatric Autism Spectrum Disorder
In-person participation required
Assessing Functional Language Development via Telehealth
Fully remote/online
Supporting nonverbal communication priorities for adults on the autism spectrum
Fully remote/online
Eye-tracking In-person Research
In-person participation required
Shape in Healthcare Study
Fully remote/online
Sleep in Children with Autism
In-person participation required
Aging in Autism
In-person participation required
Camouflaging/masking among females on the autism spectrum
Fully remote/online
Test Elevation
Fully remote/online
Development of a support program for autistic adults and their families
Fully remote/online
Identification of Biomarkers in Autism Spectrum Disorder (ASD) using Protein and Metabolite Profiling
In-person participation required
Speech and Motor Assessment Remote Protocol (SMART)
In-person participation required
TARGETING THE NEUROBIOLOGY OF RESTRICTED AND REPETITIVE BEHAVIORS IN CHILDREN WITH AUTISM USING N-ACETYLCYSTEINE: RANDOMIZED CONTROLLED TRIAL
In-person participation required
Work Chat Online
Fully remote/online
Family Collaboration on Video-Learning
Fully remote/online
GEMMA (Genome, Environment, Microbiome, and Metabolome in Autism)
Fully remote/online
Predicting Self-Care and Quality of Life in the Context of Parenting a Child with Autism Spectrum Disorder
Fully remote/online
Knowledge, Perceptions, and Use of Psychedelics among intellectually able adults with autism spectrum condition: An online survey.
Fully remote/online
Characterizing sleep physiology in ASD: a home-based study
Fully remote/online
Adult Autism Sensory Research – The Vanderbilt Sound Sensitivity Study
In-person participation required
Exploring Virtual Group Acceptance and Commitment Therapy Format on Participation of Parents of Children with Autism
Fully remote/online
RICART Adolescent to Young Adult Study (RAYS)
Fully remote/online In-person participation required
Testing the Bottom-Up vs Top-Down Imbalance Hypothesis of ASD
In-person participation required
Video Mediated Education
In-person participation required
Cognitive Aging in Mothers of Children with Autism Spectrum Disorder
Fully remote/online
The Relationship Between Dyadic Coping and Couple Satisfaction for Parents with Autistic Children
Fully remote/online
Stress and Mental Health in Parents of Autistic and Gender Diverse Adolescents
Fully remote/online
Pilot and Try-Out of the Draft TPI
Fully remote/online
Autism Spectrum Disorder Parental Attitudes Survey
Fully remote/online
Boosting Engagement and Skill Acquisition through technology and personalization: A pilot trial of enhanced transdiagnostic behavioral therapy
Fully remote/online
The neural basis of third party social interaction perception in autism
In-person participation required
Emotion Recognition in Autism
Fully remote/online
Parental Accommodation of Autism Spectrum Disorder
Fully remote/online
Therapy for Minimally Verbal Autistic Adults
In-person participation required
RISE
Fully remote/online