Share

Testing the Bottom-Up vs Top-Down Imbalance Hypothesis of ASD

February 28, 2007 - January 1, 2025

We are the TRANSCEND Research Team at Massachusetts General Hospital – thank you so much for your interest in our research! Our research is about how different areas in the brain are connected in autism compared to typically developing individuals, and is entirely non-invasive. We are currently recruiting individuals ages 14-32. The study would involve behavioral assessments, and 1-2 sessions in the MEG, a device that reads brainwaves, and is similar to EEG. We will also determine with you whether an MRI is needed. If so, it will be a very short one – about 10-15 minutes. You can read more about our studies on our website: http://transcend.mgh.harvard.edu/ We reimburse for time at the rate of $30/hr for behavioral assessments, and $70/hr for MRI/MEG visits. We also reimburse for travel expenses such as Uber and Lyft costs (up to $80 per visit) and for parking. Note also that our visit times are flexible, and we will do our best to accommodate your schedule.

What are the goals of the study?

Our research group studies brain development and associated medical conditions in healthy adults and adults with developmental disorders such as autism, an autism spectrum disorder, language impairments, attention deficit disorders, or sensory processing disorders, including misophonia. Specifically, we are trying to understand how sensory information (sight, hearing, and touch) is processed in the brain of an individual with autism spectrum or other developmental disorders as compared to a healthy individual.

What will happen during the visit or online?

The study would involve behavioral assessments, and 1-2 sessions in the MEG, a device that reads brainwaves, and is similar to EEG. We will also determine with you whether an MRI is needed. If so, it will be a very short one – about 10-15 minutes. If you self-identify as having misophonia, we will ask you to get a comprehensive audiology exam at the Mass Eye and Ear Audiology clinic affiliated with MGH, to rule out other potential auditory processing disorders.

How will this help families?

There is no direct benefit to the subject for participating in the research. We hope that the information gathered in our studies will aid in the identification, understanding, and treatment of autism.

Eligibility Criteria

Recruiting individuals who have been diagnosed with ASD, ages 14-30

View the study flyer here

Contact Information

Grace Levine – transcend@partners.org, (617) 966-9766

Research Study Website
TRANSCEND Research Team at Massachusetts General Hospital

More Research studies from this topic: Diagnosis

Autism Biomarkers Consortium for Clinical Trials
In-person participation required
Autism-relevant profiles in neurogenetic syndromes
Online web-based study
Multi-Site Validation Study of Eye Tracking-Based Measure of Autism Symptom Severity
In-person participation required
Center for Brain Disease Diagnosis at the NRI
In-person participation required Online web-based study
San Diego State University Toddler MRI Project
In-person participation required
Autism Home Videos for Children
Online web-based study
Autism Intervention Research Network on Behavioral Health
Online web-based study
Simons Searchlight
Online web-based study
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
In-person participation required
Predicting and Optimizing Language Outcomes in Minimally Verbal Children with Autism Spectrum Disorder (POLO)
In-person participation required
Adolescent Communication of Emotion Study
In-person participation required
Exploring Positive and Negative Dimensions in Autism Spectrum Disorders (EXPAND)
In-person participation required
MARBLES
In-person participation required
CHARGE
In-person participation required
Imaging Cognition and Neurodevelopment (ICAN)
In-person participation required
Infant-Caregiver Synchrony in Autism
In-person participation required
MRI Study for Prediction of ASD
In-person participation required
Walking and Talking in Autism
In-person participation required
RARE-X Data Collection Program
Online web-based study
Cognitive Functioning in Children
Online web-based study
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
In-person participation required
Pubertal, Psychosocial and Physiological Development in Females with Autism
In-person participation required
Genetics of Autism in Latinx Ancestries
In-person participation required
Social Dynamics and Early Visual Experiences
In-person participation required
WATCH Motor Development Study: Advancing Screening Tools for ASD
In-person participation required
The Investigation of Genetics Exome Research (TIGER-3)
Online web-based study In-person participation required
A Pilot Study of Transcranial Direct Current Stimulation (tDCS) in Children with Autism Spectrum Disorder (ASD)
In-person participation required
Research Studying Pimavanserin in Irritability Associated with Pediatric Autism Spectrum Disorder
In-person participation required
Mapping brain function in children with autism spectrum disorder with diffuse optical tomography
In-person participation required
Eye-tracking In-person Research
In-person participation required
Aging in Autism
In-person participation required
Camouflaging/masking among females on the autism spectrum
Online web-based study
Perceptions of Autism in a Digital Age
Online web-based study
 Satisfaction with Social Support and Future Anxiety Among Hispanic Guardians of Children with Autism/Satisfacción con el Apoyo Social y Ansiedad Futura entre Tutores Hispanos de Niños con Trastorno de Espectro Autista
Online web-based study
Development of the M-CHAT-S, a school-age extension of the Modified Checklist for Autism in Toddlers
Online web-based study
Identification of Biomarkers in Autism Spectrum Disorder (ASD) using Protein and Metabolite Profiling
In-person participation required
Perceptions of Autism Spectrum Disorder: A Sociocultural Study
Online web-based study
GEMMA (Genome, Environment, Microbiome, and Metabolome in Autism)
Online web-based study
The Impact of Hobbies on the Well-being of Autism in Adults
Online web-based study