2014 Research Findings

The following studies co-authored by ASF grantees, whose names are underlined, were published in 2014. The grants awarded by ASF to fund these studies may have been distributed in years prior to 2014.

Biology

De novo SCN2A splice site mutation in a boy with Autism spectrum disorder
Tavassoli T, Kolevzon A, Wang AT, Curchack-Lichtin J, Halpern D, Schwartz L, Soffes S, Bush L, Grodberg D, Cai G, Buxbaum JD
PubMed ID: 24650168
ASF supported this research through a Post-Doctoral Training Award to Teresa Tavassoli and a Treatment Grant to Alexander Kolevzon.

Etiologies underlying sex differences in Autism Spectrum Disorders
Schaafsma SM, Pfaff DW
PubMed ID: 24705124
ASF supported this research through a Post-Doctoral Training Award to Sara Schaafsma.

Extinction of an instrumental response: a cognitive behavioral assay in Fmr1 knockout mice
Sidorov MS, Krueger DD, Taylor M, Gisin E, Osterweil EK, Bear MF
PubMed ID: 24684608
ASF supported this research through a Fellowship Award to Michael Sidorov.

Introduction of the human AVPR1A gene substantially alters brain receptor expression patterns and enhances aspects of social behavior in transgenic mice
Charles R, Sakurai T, Takahashi N, Elder GA, Gama Sosa MA, Young LJ, Buxbaum JD
PubMed ID: 24924430
ASF supported this research through a Fellowship Award to Rhonda Charles.

Overview of Mouse Models of Autism Spectrum Disorders
Bey AL, Jiang YH
PubMed ID: 25181011
ASF supported this research through a Pre-Doctoral Training Award to Alexandra Bey.

Psychology

Attention and word learning in autistic, language delayed and typically developing children
Tenenbaum EJ, Amso D, Abar B, Sheinkopf SJ
PubMed ID: 24904503
ASF supported this research through a Post-Doctoral Training Award to Elena Tenenbaum.

Atypical cross talk between mentalizing and mirror neuron networks in autism spectrum disorder
Fishman I, Keown CL, Lincoln AJ, Pineda JA, Müller RA
PubMed ID: 24740586
ASF supported this research through a Post-Doctoral Training Award to Inna Fishman.

Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology
Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC
PubMed ID: 25538564
ASF supported this research through a Pre-Doctoral Training Award to Russell Port.

Limited fine motor and grasping skills in 6-month-old infants at high risk for autism
Libertus K, Sheperd KA, Ross SW, Landa RJ
PubMed ID: 24978128
ASF supported this research through a Post-Doctoral Training Award to Klaus Libertus.

Preliminary findings of similarities and differences in the signed and spoken language of children with autism
Shield A
PubMed ID: 25321855
ASF supported this research through an Enhancement Mini-Grant to Aaron Shield.

Scaffolded reaching experiences encourage grasping activity in infants at high risk for autism
Libertus K, Landa RJ
PubMed ID: 25295021
ASF supported this research through a Post-Doctoral Training Award to Klaus Libertus.

Underconnectivity of the superior temporal sulcus predicts emotion recognition deficits in autism
Alaerts K, Woolley DG, Steyaert J, Di Martino A, Swinnen SP, Wenderoth N
PubMed ID: 24078018
ASF provided funding support to the Autism Brain Imaging Data Exchange.

Diagnosis

Potential impact of DSM-5 criteria on autism spectrum disorder prevalence estimates
Maenner MJ, Rice CE, Arneson CL, Cunniff C, Schieve LA, Carpenter LA, Van Naarden Braun K, Kirby RS, Bakian AV, Durkin MS
PubMed ID: 24452504
ASF supported this research through a Fellowship Award to Matthew Maenner.

Quantifying the potential impact of measurement error in an investigation of autism spectrum disorder (ASD)
Heavner K, Newschaffer C, Hertz-Picciotto I, Bennett D, Burstyn I
PubMed ID: 24470431
ASF supported this research through a Post-Doctoral Training Award to Karyn Heavner.

The Sensory Perception Quotient (SPQ): development and validation of a new sensory questionnaire for adults with and without autism
Tavassoli T, Hoekstra RA, Baron-Cohen S
PubMed ID: 24791196
ASF supported this research through a Post-Doctoral Training Award to Teresa Tavassoli.

Treatment

Assessing and Improving Early Social Engagement in Infants
Koegel L, Singh A, Koegel R, Hollingsworth J, Bradshaw J
PubMed ID: 25313271
ASF supported this research through a Pre-Doctoral Training Award to Jessica Bradshaw.

Correlation of cognitive and social outcomes among children with autism spectrum disorder in a randomized trial of behavioral intervention
Locke J, Rotheram-Fuller E, Xie M, Harker C, Mandell D
PubMed ID: 24104511
ASF supported this research through a Post-Doctoral Training Award to Jill Locke.

Improvements in social and adaptive functioning following short-duration PRT program: a clinical replication
Ventola P, Friedman HE, Anderson LC, Wolf JM, Oosting D, Foss-Feig J, McDonald N, Volkmar F, Pelphrey KA
PubMed ID: 24915928
ASF supported this research through an Enhancement Mini-Grant to Pamela Ventola.