2015 Research Findings

The following studies co-authored by ASF grantees, whose names are underlined, were published in 2015. The grants awarded by ASF to fund these studies may have been distributed in years prior to 2015.

Biology

Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits
Speed HE, Kouser M, Xuan Z, Reimers JM, Ochoa CF, Gupta N, Liu S, Powell CM
PubMed ID: 26134648
ASF supported this research through a Post-Doctoral Training Award to Haley Speed.

Endocannabinoid signaling mediates oxytocin-driven social reward
Wei D, Lee D, Cox CD, Karsten CA, Pe├▒agarikano O, Geschwind DH, Gall CM, Piomelli D
PubMed ID: 26504214
ASF supported this research through a Pre-Doctoral Training Award to Donghui Wei.

Moving from capstones toward cornerstones: successes and challenges in applying systems biology to identify mechanisms of autism spectrum disorders
Kopp N, Climer S, Dougherty JD
PubMed ID: 26500678
ASF supported this research through a Pre-Doctoral Training Award to Nathan Kopp.

Sex differences in cortical volume and gyrification in autism
Schaer M, Kochalka J, Padmanabhan A, Supekar K, Menon V
PubMed ID: 26146534
ASF supported this research through a Post-Doctoral Training Award to Aarthi Padmanabhan.

Psychology

A Simulation Study of Categorizing Continuous Exposure Variables Measured with Error in Autism Research: Small Changes with Large Effects
Heavner K, Burstyn I
PubMed ID: 26305250
ASF supported this research through a Post-Doctoral Training Award to Karyn Heavner.

Atypical Visual Saliency in Autism Spectrum Disorder Quantified through Model-Based Eye Tracking
Wang S, Jiang M, Duchesne XM, Laugeson EA, Kennedy DP, Adolphs R, Zhao Q
PubMed ID: 26593094
ASF supported this research through a Post-Doctoral Training Award to Shuo Wang.

Deconstructing and Reconstructing Theory of Mind
Schaafsma SM, Pfaff DW, Spunt RP, Adolphs R
PubMed ID: 25496670
ASF supported this research through a Post-Doctoral Training Award to Sara Schaafsma.

Inhibition-Based Biomarkers for Autism Spectrum Disorder
Levin AR, Nelson CA
PubMed ID: 25813603
ASF supported this research through a Post-Doctoral Training Award to April Levin.

Pooling Bio-Specimens in the Presence of Measurement Error and Non-Linearity in Dose-Response: Simulation Study in the Context of a Birth Cohort Investigating Risk Factors for Autism Spectrum Disorders
Heavner K, Newschaffer C, Hertz-Picciotto I, Bennett D, Burstyn I
PubMed ID: 26610532
ASF supported this research through a Post-Doctoral Training Award to Karyn Heavner.

Prospective MEG biomarkers in ASD: pre-clinical evidence and clinical promise of electrophysiological signatures
Port RG, Anwar AR, Ku M, Carlson GC, Siegel SJ, Roberts TP
PubMed ID: 25745372
ASF supported this research through a Pre-Doctoral Training Award to Russell Port.

Reduced Integration and Differentiation of the Imitation Network in Autism: A Combined Functional Connectivity Magnetic Resonance Imaging and Diffusion-Weighted Imaging Study
Fishman I, Datko M, Cabrera Y, Carper RA, M├╝ller RA
PubMed ID: 26418284
ASF supported this research through a Post-Doctoral Training Award to Inna Fishman.

Sex and gender differences in autism spectrum disorder: summarizing evidence gaps and identifying emerging areas of priority
Halladay AK, Bishop S, Constantino JN, Daniels AM, Koenig K, Palmer K, Messinger D, Pelphrey K, Sanders SJ, Singer AT, Taylor JL, Szatmari P
PubMed ID: 26075049
ASF Chief Science Officer Alycia Halladay and ASF President Alison Singer co-authored this publication.

The Use of Sign Language Pronouns by Native-Signing Children with Autism
Shield A, Meier RP, Tager-Flusberg H
PubMed ID: 25643865
ASF supported this research through an Enhancement Mini-Grant to Aaron Shield.

Variation in functional connectivity along anterior-to-posterior intraparietal sulcus, and relationship with age across late childhood and adolescence
Vinette SA, Bray S
PubMed ID: 25951196
ASF provided funding support to the Autism Brain Imaging Data Exchange.

Vocal Coordination During Early Parent-Infant Interactions Predicts Language Outcome in Infant Siblings of Children with Autism Spectrum Disorder
Northrup JB, Iverson JM
PubMed ID: 26345517
ASF supported this research through a Pre-Doctoral Training Award to Jessie Northrup.

Treatment

Complementary and alternative treatments for autism part 2: identifying and avoiding non-evidence-based treatments
Singer A, Ravi R
PubMed ID: 25901708
ASF President Alison Singer co-authored this publication.

Feasibility and effectiveness of very early intervention for infants at-risk for autism spectrum disorder: a systematic review
Bradshaw J, Steiner AM, Gengoux G, Koegel LK
PubMed ID: 25218848
ASF supported this research through a Pre-Doctoral Training Award to Jessica Bradshaw.

Heterogeneity of neural mechanisms of response to pivotal response treatment
Ventola P, Yang DY, Friedman HE, Oosting D, Wolf J, Sukhodolsky DG, Pelphrey KA
PubMed ID: 25370452
ASF supported this research through an Enhancement Mini-Grant to Pamela Ventola.

Naturalistic Developmental Behavioral Interventions: Empirically Validated Treatments for Autism Spectrum Disorder
Schreibman L, Dawson G, Stahmer AC, Landa R, Rogers SJ, McGee GG, Kasari C, Ingersoll B, Kaiser AP, Bruinsma Y, McNerney E, Wetherby A, Halladay A
PubMed ID: 25737021
ASF Chief Science Officer Alycia Halladay co-authored this publication.

Pivotal Response Treatment: Case Reports
Ventola P, Friedman H, Oosting D
PubMed ID: 27337818
ASF supported this research through an Enhancement Mini-Grant to Pamela Ventola.

Toward optimal outcome following pivotal response treatment: a case series
Ventola P, Oosting DR, Keifer CM, Friedman HE
PubMed ID: 25745373
ASF supported this research through an Enhancement Mini-Grant to Pamela Ventola.

Services

A tangled web: the challenges of implementing an evidence-based social engagement intervention for children with autism in urban public school settings
Locke J, Olsen A, Wideman R, Downey MM, Kretzmann M, Kasari C, Mandell DS
PubMed ID: 25526835
ASF supported this research through a Post-Doctoral Training Award and an Early Career Award to Jill Locke.

All Together Now: Measuring Staff Cohesion in Special Education Classrooms
Kratz HE, Locke J, Piotrowski Z, Ouellette RR, Xie M, Stahmer AC, Mandell DS
PubMed ID: 26213443
ASF supported this research through an Early Career Award to Jill Locke.

Clearing Hurdles: The Challenges of Implementation of Mental Health Evidence-Based Practices in Under-resourced Schools
Eiraldi R, Wolk CB, Locke J, Beidas R
PubMed ID: 26336512
ASF supported this research through an Early Career Award to Jill Locke.

One-to-One Assistant Engagement in Autism Support Classrooms
Azad GF, Locke J, Downey MM, Xie M, Mandell DS
PubMed ID: 26807003
ASF supported this research through an Enhancement Mini-Grant to Gazi Azad and an Early Career Award to Jill Locke.