2019 Research Findings

The following studies co-authored by ASF grantees, whose names are underlined, were published in 2019. The grants awarded by ASF to fund these studies may have been distributed in years prior to 2019.

Biology and Biomarkers

Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioral and myelinalterations rescuable by a remyelinating drug
Barak B, Zhang Z, Liu Y, Nir A, Trangle SS, Ennis M, Levandowski KM, Wang D, Quast K, Boulting GL, Li Y, Bayarsaihan D10, He Z, Feng G
PubMed ID: 31171854
ASF supported this research through a Post-Doctoral Training Award to Boaz Barak. 

Deletion of the KH1 Domain of Fmr1 Leads to Transcriptional Alterations and Attentional Deficits in Rats
Golden CEM, Breen MS, Koro L, Sonar S, Niblo , Browne A, Burlant N, Di Marino D, De Rubeis S, Baxter MG, Buxbaum JD, Harony-Nicolas H
PubMed ID: 30877790
ASF supported this research through a Post-Doctoral Training Award to Michael S. Breen.

CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes
Fricano-Kugler C, Gordon A, Shin G, Gao K, Nguyen J, Berg J, Starks M, Geschwind DH
PubMed ID: 31198525
ASF supported this research through a Pre-Doctoral Fellowship Award to Aaron Gordon.

Do Sensitive Periods Exist for Exposure to Adversity?
Gabard-Durnam LJ, McLaughlin KA
PubMed ID: 31199787
ASF supported this research through a Post-Doctoral Training Award to Laurel Gabard-Durnam.

Reliability of human cortical organoid generation
Yoon SJ, Elahi LS, Pașca AM, Marton RM, Gordon A, Revah O, Miura Y, Walczak EM, Holdgate GM, Fan HC, Huguenard JR, Geschwind DH, Pașca SP
PubMed ID: 30573846
ASF supported this research through a Pre-Doctoral Training Award to Aaron Gordon.

Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion
Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY
PubMed ID: 31197172
ASF supported this research through a Pre-Doctoral Training Award to Jason Keil.

Setd5 haploin sufficiency alters neuronal network connectivity and leads to autistic-like behaviors in mice
Moore SM, Seidman JS, Ellegood J, Gao R, Savchenko A, TroutmanTD, Abe Y, Stender J, Lee D, Wang S, Voytek B, Lerch JP, Suh H, Glass CK, Muotri AR
PubMed ID: 30655503
ASF and the Rett Syndrome Research Trust supported this research through a Pre-Doctoral Training Award to Spencer Moore.

Heterodimerization of UNC-13/RIM regulates synaptic vesicle release probability but not priming in C. elegans
Liu H, Li L, Nedelcu D, Hall Q, Zhou L, Wang W, Yu Y, Kaplan JM, Hu Z
PubMed ID: 30802206
ASF supported this research through a Post-Doctoral Training Award to Daniel Nedelcu.

Parvalbumin Cell Ablation of NMDA-R1 Leads to Altered Phase, But Not Amplitude, of Gamma-Band Cross-Frequency Coupling
Port RG, Berman JI, Liu S, Featherstone RE, Roberts TPL, Siegel SJ
PubMed ID: 30588822
ASF supported this research through a Pre-Doctoral Training Award to Russell Port.

Use of Longitudinal EEG Measures in Estimating Language Development in Infants With and Without Familial Risk for Autism Spectrum Disorder
Wilkinson CL, Gabard-Durnam LJ, Kapur K, Tager-Flusberg H
DOI: 10.1162/nol_a_00002
ASF supported this research through Post-Doctoral Training Awards to Carol Wilkinson and Lauren Gabard-Durnam

Atypical Local and Distal Patterns of Occipito-frontal Functional Connectivity are Related to Symptom Severity in Autism
Jao Keehn RJ, Nair S, Pueschel EB, Linke AC, Fishman I, Müller RA
PubMed ID: 30137241
ASF supported this research through a Post-Doctoral Training Award to Inna Fishman

Sex-Based Analysis of De Novo Variants in Neurodevelopmental Disorders
Turner TN, Wilfert AB, Bakken T, Bernier RA, Pepper MR, Zhang Z, Torene RI, Retterer K, Eichler EE
PubMed ID: 31785789
ASF supported this research through a Post-Doctoral Training Award to Tychele Turner

Differences in the Late Positive Potential and P300 to Emotional Faces in Individuals with Autism Spectrum Disorder
Keifer CM, Hauschild KM, Nelson BD, Hajcak G, Lerner MD
PubMed ID: 31486998
ASF supported this research through a Pre-Doctoral Training Award to Cara Keifer

Discrete electrocortical predictors of anxiety and anxiety-related treatment response in youth with autism spectrum disorder
Kang E, Clarkson T, Keifer CM, Rosen TE, Lerner MD
PubMed ID: 31158425
ASF supported this research through a Pre-Doctoral Training Award to Cara Keifer

Services

Computational Linguistics for Enhancing Scientific Reproducibility and Reducing Healthcare Inequities
Parish-Morris J
Anthology ID: W19-3011
ASF supported this research through a Post-Doctoral Training Award to Julia Parish-Morris.

Factors impacting employment for people with autism spectrum disorder: A scoping review
Scott M, Milbourn B, Falkmer M, Black M, Bӧlte S, Halladay A, Lerner M, Taylor JL, Girdler S
PubMed ID: 30073870
ASF supported this research through the Employment Policy Brief

It’s messy but real: a pilot study of the implementation of a social engagement intervention for children with autism in schools
Locke J, Kang‐Yi C, Pellecchia M, Mandell DS
DOI: 10.1111/1471-3802.12436
ASF supported this research through an Early Career Award to Jill Locke.

Brief Report: Examining the Association Between Classroom Social Network Inclusion and Playground Peer Engagement Among Children With Autism Spectrum Disorders
Santillan, L, Frederick L, Gilmore S, Locke J
DOI: 10.1177/1088357619838275
ASF supported this research through an Early Career Award to Jill Locke.

Employment policy and autism: Analysis of state workforce innovation and opportunity act (WIOA) implementation plans
Roux AM, Garfield T, Shattuck PT
DOI: 10.3233/jvr-191046
ASF supported this research through an Accelerator Award to Anne M. Roux.

Perspectives of key stakeholders on employment of autistic adults across the united states, australia, and sweden
Black MH, Mahdi S, Milbourn B, Thompson C, D’Angelo A, Ström E, Falkmer M, Falkmer T, Lerner M, Halladay A, Gerber A, Esposito C, Girdler S, Bölte S
PubMed ID: 31276308
ASF supported this research through the unemployment policy brief.

Diagnosis

Early motor abilities in infants at heightened vs. low risk for ASD: A Baby Siblings Research Consortium (BSRC) study
Iverson JM, Shic F, Wall CA, Chawarska K, Curtin S, Estes A, Gardner JM, Hutman T, Landa RJ, Levin AR, Libertus K, Messinger DS, Nelson CA, Ozonoff S, Sacrey LR, Sheperd K, Stone WL, Tager-Flusberg HB, Wolff JJ, Yirmiya N1, Young GS
PubMed ID: 30628809
ASF supported this research through support of the BSRC

Trajectories of Posture Development in Infants With and Without Familial Risk for Autism Spectrum Disorder
Leezenbaum NB, Iverson JM
PubMed ID: 31079276
ASF supported this research through a Pre-Doctoral Award to Nina B. Leezenbaum.

Treatment

A Structured Intervention to Increase Response Allocation to Instructional Settings for Children with Autism Spectrum Disorder
Cariveau T, Shillingsburg MA, Alamoudi A, Thompson T, Bartlett B, Gillespie S, Scahill L
DOI: 10.1007/s10864-019-09340-x
ASF supported this research through a Post-Doctoral Training Award to Tom Cariveau.

Assessment and Treatment of Problem Behavior Maintained by Termination of Interruptions
Cariveau T, Miller SJ, Call NA, Alvarez J
PubMed ID: 30727805
ASF supported this research through a Post-Doctoral Training Award to Tom Cariveau.

Brief Report: Feasibility and Preliminary Efficacy of a Behavioral Intervention for Minimally Verbal Girls with Autism Spectrum Disorder
Cariveau T, Shillingsburg MA, Alamoudi A, Thompson T, Bartlett B, Gillespie S, Scahill L
PubMed ID: 30607780
ASF supported this research through a Post-Doctoral Training Award to Tom Cariveau.

Psychology

Linguistic markers of autism in girls: evidence of a “blended phenotype” during storytelling
Boorse J, Cola M, Plate S, Yankowitz L, Pandey J, Schultz RT, Parish-Morris J
PubMed ID: 30962869
ASF supported this research through a Post-Doctoral Training Award to Julia Parish-Morris.

Initial eye gaze to faces and its functional consequence on face identification abilities in autism spectrum disorder
Schauder KB, Park WJ, Tsank Y, Eckstein MP, Tadin D, Bennetto L
PubMed ID: 31883518
ASF supported this research through a Pre-Doctoral Training Award to Woon Ju Park

Automatic Detection of Autism Spectrum Disorder in Children Using Acoustic and Text Features from Brief Natural Conversations
Cho S, Liberman M, Ryant N, Cola M, Schultz RT, Parish-Morris J
DOI: 10.21437/Interspeech.2019-1452
ASF supported this research through a Post-Doctoral Training Award to Julia Parish-Morris.

Visual attention to faces in children with autism spectrum disorder: are there sex differences?
Harrop C, Jones D, Zheng S, Nowell S, Schultz R, Parish-Morris J
PubMed ID: 31297179
ASF supported this research through a Post-Doctoral Training Award to Julia Parish-Morris.