Autism Science

Effects of a Brief Early Start Denver Model (ESDM)-Based Parent Intervention on Toddlers at Risk for Autism Spectrum Disorders: A Randomized Controlled Trial

Source: 
J Am Acad Child Adolesc Psychiatry
Date Published: 
October, 2012
Year Published: 
2012
Abstract: 

This study was carried out to examine the efficacy of a 12-week, low-intensity, parent-delivered intervention for toddlers at risk for autism spectrum disorders (ASD) aged 14 to 24 months and their families.

Cholesterol connection to Rett Syndrome

Source: 
Nature Genetics
Date Published: 
July 28, 2013
Abstract: 

Professor Monica Justice has written a study on a connection between cholesterol and Rett Syndrome. Statin drugs, known to lower cholesterol, were shown to increase mobility, overall health scores, and lifespan in mice with Rett Syndrome.

Group Cognitive Behavior Therapy for Children with High-Functioning Autism Spectrum Disorders and Anxiety: A Randomized Trial

Source: 
J Child Psychol Psychiatry
Date Published: 
April, 2012
Year Published: 
2012
Abstract: 

Fifty children with high-functioning Autism Spectrum Disorder (ASD) and anxiety were randomized to group Cognitive Behavioral Theory (CBT) or treatment-as-usual (TAU) for 12 weeks.

Melatonin for Sleep in Children with Autism: A Controlled Trial Examining Dose, Tolerability, and Outcomes

Source: 
J Autism Dev Disord
Date Published: 
August, 2012
Year Published: 
2012
Abstract: 

Supplemental melatonin has shown promise in treating sleep onset insomnia in children with autism spectrum disorders (ASD).

Teacher-Implemented Joint Attention Intervention: Pilot Randomized Controlled Study for Preschoolers with Autism

Source: 
J Consult Clin Psychol
Date Published: 
August, 2012
Year Published: 
2012
Abstract: 

This study investigated the effectiveness of public preschool teachers implementing a validated intervention (the Joint Attention and Symbolic Play/Engagement and Regulation intervention; JASP/ER) on a core deficit of autism, initiating joint attention.

The Effect of Levetiracetam on Focal Nocturnal Epileptiform Activity During Sleep-A Placebo-Controlled Double-Blind Cross-Over Study

Source: 
Epilepsy Behav
Date Published: 
May, 2012
Year Published: 
2012
Abstract: 

This study was designed to assess AED effect in a placebo-controlled double-blind cross-over study. Levetiracetam (LEV) was chosen based on clinical evidence.

Making the Connection: Randomized Controlled Trial of Social Skills at School for Children with Autism Spectrum Disorders

Source: 
J Child Psychol Psychiatry
Date Published: 
April, 2012
Year Published: 
2012
Abstract: 

This study compared two interventions for improving the social skills of high functioning children with autism spectrum disorders in general education classrooms. One intervention involved a peer-mediated approach (PEER) and the other involved a child-assisted approach (CHILD).

Longitudinal Follow-Up of Children with Autism Receiving Targeted Interventions on Joint Attention and Play

Source: 
J Am Acad Child Adolesc Psychiatry
Date Published: 
May, 2012
Year Published: 
2012
Abstract: 

This study examines the cognitive and language outcomes of children with an autism spectrum disorder (ASD) over a 5-year period after receiving targeted early interventions that focused on joint attention and play skills.

A Randomized Controlled Trial of Preschool-Based Joint Attention Intervention for Children with Autism

Source: 
J Child Psychol Psychiatry
Date Published: 
January, 2012
Year Published: 
2012
Abstract: 

Assess the effects of a preschool-based Joint Attention (JA)-intervention.

A Double-Blind Placebo-Controlled Trial of Fluoxetine for Repetitive Behaviors and Global Severity in Adult Autism Spectrum Disorders

Source: 
Am J Psychiatry
Date Published: 
March, 2012
Year Published: 
2012
Abstract: 

The effects of fluoxetine and placebo on repetitive behaviors and global severity were compared in adults with autism spectrum disorders (ASDs).