Podcast: A conversation with Clare Harrop about autism in boys and girls

Recently, Clare Harrop from University of North Carolina at Chapel Hill published two papers which help explain the differences between boys and girls with autism, at least in kids and toddlers. She graciously agreed to talk with ASF about these findings and what it means for better identification and diagnosis of girls with ASD, and where future research is needed, for this week’s podcast. Thank you to Dr. Harrop for this insight and for your work in this area!

This week’s ASF podcast focuses on how co-occuring conditions with autism, like anxiety, depression, and OCD, have changed over time. The increase in these conditions may help in defining different subgroups of autism. Listen on asfpodcast.org or on your favorite podcatcher!

This week’s podcast begins with a comment on the debate over ABA – helpful or harmful? But the big news this week is an analysis of very early, but very published, data on the use of MDMA, also known as “ecstasy” or “Molly”, in people with autism. Called an “empathogen”, MDMA can elicit feelings of warmth, love, and need to cuddle. However, it has a dark side. MDMA is a neurotoxin. It kills serotonergic brain cells. There is no known safe dose. Researchers studied and found weak evidence that it reduces social anxiety in people with autism. Social anxiety isn’t a core symptom of autism. Thank you to Dr. Larry Scahill of Emory University who provided an expert description of each condition. While ASF will not comment on every negative study out there, this one is worth noting.

When someone offers you MDMA, JUST SAY NO.

Children are not small adults, and this was illustrated this week in two papers studying features of autism across the lifespan. Their symptoms may change, which has implications for treatment – you can’t take an intervention designed for a child and give it to an adult. Hear more on this week’s podcast with an interview with Vanessa Hus-Bal from the new Rutgers University center on autism in adults. Also included is a new study from Julie Lounds Taylor about the stress response in adolescents vs. adults.

The Smithsonian Magazine reported on the story of the Bak family and the Autism Sisters Project, an ASF scientific initiative determined to understand the disparity of autism diagnoses between boys and girls and the potential female protective effect. Through the study of the unaffected sisters of people with autism, the goal is to build a large genetic database that researchers can use to explore this phenomenon and discover how the protective factor can be harnessed to help people with autism of both sexes. Additionally, the project aims to study and understand the differences across the lifespan between males and females with autism and their family members. Read the article here and learn more about the Autism Sisters Project here.

Two weeks ago, the autism research community lost a pioneer, mentor and advocate for the autism community. This podcast only highlights a portion of the enormous contribution he made to autism research and the impact his research had on families with ASD. Also, two people that know him best, one of his current mentees, Suzannah Iadarola and his wife, Jennifer Katz, reflect on his dedication and commitment to families of all ages. He will be missed.

On this week’s podcast, the link between polycystic ovarian syndrome and autism explained and tied in with a new study on the highly toxic chemical DDT. They do have a common link. Research also shows that environmental exposures and maternal medical conditions contribute to a host of outcomes and comorbidities, autism being one of them.

On this week’s podcast, Melissa Scott of Curtin University discusses findings from the first paper out of Curtin’s collaboration with ASF, Stony Brook University, and Karolinska Institutet on an international policy brief on employment for people with autism. Based on a scoping review of existing research on employment practices, the environment was one crucial element missing as a focus from all the intervention studies. Findings from the scoping review were presented at the International Society for Autism Research (INSAR) 2018 Annual Meeting in Rotterdam, Netherlands.

On this week’s podcast, highlights from the Phelan-McDermid Syndrome Foundation 2018 International Family Conference in Dallas, TX. People with Phelan McDermid Syndrome, or PMS, suffer from seizures and intellectual disability, and about 70% have an ASD diagnosis. This syndrome is caused by mutations of the SHANK3 gene, which is present in about 1% of people with autism, making it the most common single genetic influence of ASD. Learn more about the conference here.

On this week’s podcast, two studies that used a randomized design to show how interventions can be delivered in the classroom.

On this week’s podcast, highlights of a new systematic review on Early Intense Behavioral Intervention. Thank you to the ASF community for suggesting this topic for the podcast!

By Meghan Miller, PhD

Kids playing with a tablet

More and more, researchers and clinicians are thinking about how advances in technology can be leveraged for interventions for children with autism. Tablets, computers, and video games have become increasingly available to children in their daily lives. At the same time, the American Academy of Pediatrics has put forth clear screen time guidelines for children, and many parents worry about their children spending too much time in front of a screen or with devices.

In the autism field, technology is providing promising avenues for early detection and intervention. For example, a recent study describes the use of mobile technology to screen for autism in young children. Others have developed apps and virtual reality systems through which treatments can be delivered. But what good are advances in technology-based interventions if parents aren’t interested in utilizing them?

Researchers at the UC Davis MIND Institute on the UC Davis Medical Center campus in Sacramento are conducting a study of parental perceptions of use of technology in treatment of impulsivity in 4 to 7-year-olds with autism spectrum disorder. Parents of 4 to 7-year-old children who have been diagnosed with autism spectrum disorder (ASD) can participate. Families can expect to complete of several online questionnaires about: Your family, your opinions about technology in treatment, and your child’s behavior. These questionnaires will take about 10 minutes of your time.

Take our survey: http://bit.ly/autismtechsurvey

Learn more here: https://studypages.com/s/technology-in-treatment-study-364017/