Share

Aging in Autism

August 25, 2022 - August 25, 2025

This project focuses on neurobiological aspects of aging in ASD that has promise of an immediate and direct impact on several of critical issues for this group. We hypothesize that individuals with ASD will have an exacerbation of deficits beyond normal aging, as evidenced in significantly lower scores on tests affected by aging (e.g., executive) along with neuroanatomical markers of dysfunction, and relative preservation of function sub served by more posterior brain regions (semantic memory and local detail processing). Our objective is to produce comprehensive cognitive, behavioral, and neuroimaging data on a set of well-characterized older ASD individuals who can be used as a reference for clinical diagnosis, therapeutics, and care plans.

What are the goals of the study?

As the first diagnosed Autism Spectrum Disorder (ASD) adults are aging, it is important that we understand the impact of aging on autistic adults so that we may inform strategies for independent living and improved health. By studying the aging brain in autistic adults and non-autistic adults, we can create strategies to inform interventions and improve health.

What will happen during the visit or online?

Participants are asked to completed a 90 minute MRI that includes some functional tasks and some resting. Participants are also asked to complete about 3-4 hours of cognitive testing. Participants over the age of 40 are invited to come back every 2 years to repeat the testing.

How will this help families?

We are hoping to inform strategies for independent living and improved health for autistic adults as they age. This will hopefully alleviate some burden parents and caregivers carry as they are concerned about the futures of the autistic individuals they currently support.

Eligibility Criteria

We are interested in adults 40 years of age and older with ASD, those who suspect they have ASD, and those who don’t suspect they have ASD. We require the following: adults have a minimum IQ of 70, are right-handed, and have had no significant head trauma (loss of consciousness as a result of head injury in the last 10 years).

Contact Information

Shanna Delaney – sdelane3@asu.edu

 

Research Study Website
Autism and Brain Aging Lab

More Research studies from this topic: Interventions

Autism Biomarkers Consortium for Clinical Trials
In-person participation required
Transcranial Magnetic Stimulation (TMS)
In-person participation required
Generating Effectiveness Mechanisms in RUBI (GEMs in RUBI)
In-person participation required
Language and brain development in baby siblings of children with autism
In-person participation required
A treatment for SETD5 subtype of autism
Online web-based study
NEUROIMAGING PREDICTORS OF IMPROVEMENT TO PIVOTAL RESPONSE TREATMENT (PRT) IN YOUNG CHILDREN WITH AUTISM
In-person participation required
Center for Brain Disease Diagnosis at the NRI
Online web-based study In-person participation required
Neural basis of social cognition in youth with ASD and psychosis
In-person participation required
Neurodevelopmental Sleep Study
In-person participation required
Exploring Mechanisms of Change in a Pilot Trial of the RUBI Program in Educational Settings
Online web-based study
The Brain Basis of Social Attention in ASD and Intellectual Disability
In-person participation required
Autism Intervention Research Network on Behavioral Health
Online web-based study
Simons Searchlight
Online web-based study
LISTEN: Electrophysiological correlates of language processing in minimally verbal children with neurodevelopmental disorders
In-person participation required
The Autism Biomarkers Consortium for Clinical Trials: Confirmation Study
In-person participation required
Online Promoting Resilience in Teens with ASD
Online web-based study
Pivotal Response Treatment for Children with Autism Spectrum Disorders
In-person participation required
Exploring Positive and Negative Dimensions in Autism Spectrum Disorders (EXPAND)
In-person participation required
ECHO
In-person participation required
Imaging Cognition and Neurodevelopment (ICAN)
In-person participation required
Infant-Caregiver Synchrony in Autism
In-person participation required
MRI Study for Prediction of ASD
In-person participation required
Walking and Talking in Autism
In-person participation required
What do you Eat?
Online web-based study
RARE-X Data Collection Program
Online web-based study
Pubertal, Psychosocial and Physiological Development in Females with Autism
In-person participation required
A Strength-Based Intervention to Improve Job Interview Skills in Young Adults (KF-STRIDE)
Online web-based study
Caregiver-Endorsed Strategies for the Treatment of Sensory Reactivity Symptoms in Children with Neurodevelopmental Disorders
Online web-based study
Social Dynamics and Early Visual Experiences
In-person participation required
Assessing Motor Control across different Sensory Environments in Individuals with and without Autism Spectrum Disorder
In-person participation required
Sensory Over-Responsivity Propranolol Pilot
In-person participation required
TMS in ASD for Sensory Over-Responsiveness
In-person participation required
The neuroanatomical basis for face processing deficits in autism spectrum disorder
In-person participation required
Investigating neurocognitive profiles in parents of children with autism and anorexia
Online web-based study
Cannabidivarin (CBDV) vs. Placebo in Children with Autism Spectrum Disorder (ASD)
In-person participation required
Infant Robot Interaction
In-person participation required
Family-Implemented Treatment for Behavioral Inflexibility (FITBI) Project
Online web-based study
Autistic Adolescents’ Perspectives on Behavioral Interventions
Online web-based study In-person participation required
The Investigation of Genetics Exome Research (TIGER-3)
Online web-based study In-person participation required
A Pilot Study of Transcranial Direct Current Stimulation (tDCS) in Children with Autism Spectrum Disorder (ASD)
In-person participation required
Evaluating Efficacy of GuessWhat Mobile System
Online web-based study
Assessing Functional Language Development via Telehealth
Online web-based study
Supporting nonverbal communication priorities for adults on the autism spectrum
Online web-based study
SMASS
Online web-based study
Mapping brain function in children with autism spectrum disorder with diffuse optical tomography
In-person participation required
Telehealth Mindfulness-based Intervention for Adolescents with Autism Spectrum Disorder and their Caregivers
Online web-based study
Children Learning Language Collaboration Project
In-person participation required
School Absenteeism in Autistic Youth
Online web-based study